Fluindione, a compound identified by CAS number 957-56-2, is renowned for its potent Vitamin K antagonist activity. This biological function is central to its application in various fields, particularly in hematologic research and the development of anticoagulant therapies. The Vitamin K antagonist mechanism of action involves Fluindione interfering with the crucial Vitamin K cycle within the liver. Specifically, it inhibits the enzyme Vitamin K epoxide reductase (VKOR), which is essential for recycling oxidized Vitamin K back to its reduced, active form. This active form of Vitamin K is a cofactor required for the gamma-carboxylation of specific glutamic acid residues in several blood clotting factors, including Factors II, VII, IX, and X, as well as proteins C and S.

By blocking VKOR, Fluindione effectively depletes the pool of active Vitamin K, leading to the production of under-carboxylated and non-functional clotting factors. This ultimately results in a reduced capacity of the blood to coagulate, a critical effect for patients with thrombotic disorders. Understanding this precise Vitamin K antagonist mechanism of action allows researchers to effectively utilize Fluindione in their studies, whether for evaluating new anticoagulant drug candidates or for investigating the complex pathways of hemostasis. As a leading supplier in China, we are committed to providing Fluindione that meets exacting purity standards, ensuring that experimental results are accurate and reproducible. The price of such research-grade chemicals reflects their quality and the rigorous processes involved in their production.

The significance of Fluindione extends beyond its direct use as a hematologic agent. It serves as a valuable reference standard and a pharmaceutical intermediate for chemists and pharmacologists exploring new drug targets and therapeutic strategies. The ability to accurately model the Vitamin K antagonist mechanism of action using Fluindione allows for the development of more targeted and effective treatments. Our dedication as a manufacturer in China to producing high-quality Fluindione supports these critical research efforts, providing scientists with the reliable materials they need to advance their work. This focus on quality is what defines us as a trusted source for chemical research.

In essence, Fluindione (CAS 957-56-2) offers a profound window into the mechanisms of blood coagulation. Its well-defined Vitamin K antagonist mechanism of action makes it an invaluable tool for scientific exploration, from basic research to the development of clinical applications. We are proud to be a part of this scientific advancement by supplying high-quality Fluindione to researchers worldwide.