For chemists and researchers engaged in organic synthesis, understanding the precise chemical properties and application scope of key intermediates is vital. Fmoc-4-carboxymethyl-piperazine (CAS 180576-05-0) is one such compound, widely recognized for its utility in peptide synthesis and as a versatile building block in medicinal chemistry. As a dedicated manufacturer and supplier, we provide high-purity Fmoc-4-carboxymethyl-piperazine, enabling seamless integration into various synthetic pathways. This article explores its fundamental chemical characteristics and its significant applications, highlighting why sourcing this compound from a reliable source is crucial for successful research outcomes.

The molecular structure of Fmoc-4-carboxymethyl-piperazine (C21H22N2O4) confers a molecular weight of 366.41 g/mol. This compound typically presents as an off-white to white solid, indicating a high degree of purity, which is essential for sensitive synthetic reactions. The presence of the Fmoc protecting group is central to its function in peptide synthesis. This group shields the amine functionality of the amino acid derivative, preventing unwanted reactions during coupling steps. Its base-lability allows for selective deprotection using mild reagents like piperidine, a critical feature for building complex peptide sequences without compromising the integrity of the growing chain. For researchers needing to buy Fmoc-4-carboxymethyl-piperazine, understanding these chemical properties ensures they can effectively plan and execute their syntheses.

The applications of Fmoc-4-carboxymethyl-piperazine are predominantly found in the field of peptide chemistry. It serves as a valuable building block for incorporating a functionalized piperazine moiety into peptides, which can be used to create peptidomimetics, modify solubility, or introduce specific binding sites. Beyond peptide synthesis, its unique structure makes it a useful intermediate in the broader scope of organic synthesis and drug discovery. Medicinal chemists can leverage its properties to design novel small molecules, probes, and drug candidates. The carboxymethyl group offers a convenient handle for further functionalization or conjugation, expanding its utility in areas such as bioconjugation or the development of targeted drug delivery systems. Sourcing from a reputable supplier in China, such as ourselves, guarantees access to material with the necessary purity (≥ 98% HPLC) to achieve reliable synthetic results.

As a manufacturer, we emphasize the importance of quality control to ensure that our Fmoc-4-carboxymethyl-piperazine meets the stringent requirements of synthetic chemists. The stability of the Fmoc group, coupled with the reactive potential of the carboxymethyl group and the structural features of the piperazine ring, makes this compound a highly sought-after intermediate. We offer competitive pricing and a secure supply chain, facilitating its acquisition for research purposes. To inquire about pricing or place an order for Fmoc-4-carboxymethyl-piperazine, prospective buyers are encouraged to contact our sales department. Access to detailed product specifications and safety data sheets is readily available to support your procurement process.

In conclusion, Fmoc-4-carboxymethyl-piperazine is a cornerstone reagent for those involved in advanced organic synthesis, particularly in peptide and medicinal chemistry. Its well-defined chemical properties and versatile applications make it indispensable for creating complex molecules. We are committed to being your trusted supplier, offering high-purity Fmoc-4-carboxymethyl-piperazine with competitive pricing. Contact us today to secure this essential chemical building block and advance your synthetic research endeavors.