For professionals engaged in peptide synthesis, drug development, and related chemical research, the choice of reagents is critical for success. N-alpha-Fmoc-N-epsilon-(4-methyltrityl)-L-lysine, or Fmoc-Lys(Mtt)-OH, is a widely used amino acid derivative whose technical specifications directly impact its performance in synthesis. Understanding these specifications and knowing where to source high-quality material are essential for optimizing research outcomes.

The key technical specifications for Fmoc-Lys(Mtt)-OH typically include its chemical identity, purity, and physical properties. Chemically, it is defined by its molecular formula (C41H40N2O4) and molecular weight (approximately 624.77 g/mol). Its CAS number, 167393-62-6, serves as a unique identifier in chemical databases and literature. Purity is a paramount concern, with suppliers usually specifying purity levels of ≥98% or even ≥99% as determined by HPLC. High purity ensures that side reactions are minimized and that the final synthesized peptide has the expected structure and efficacy.

Physically, Fmoc-Lys(Mtt)-OH is typically described as a white to off-white powder. Its melting point often falls within a range, such as 140 °C (with decomposition), indicating its solid state and thermal stability under standard storage conditions. The solubility in common organic solvents like DCM, DMF, or DMSO is also an important factor for synthetic chemists, dictating the choice of reaction media. Optical activity, such as the specific rotation [a]D20, is measured to confirm the correct enantiomeric form (L-lysine) is present, which is crucial for biologically active peptides.

When sourcing Fmoc-Lys(Mtt)-OH, it is vital to choose suppliers who can guarantee consistent quality and reliable supply. Companies like NINGBO INNO PHARMCHEM CO.,LTD. are recognized for providing high-grade Fmoc-amino acids, including Fmoc-Lys(Mtt)-OH, to the scientific community. These suppliers often provide comprehensive documentation, such as Certificates of Analysis (CoA) and Safety Data Sheets (SDS), which detail product specifications, handling precautions, and storage recommendations. The CoA confirms the batch-specific purity and other critical parameters, while the SDS ensures safe laboratory practices.

For researchers and manufacturers, procuring Fmoc-Lys(Mtt)-OH from trusted sources like NINGBO INNO PHARMCHEM CO.,LTD. is not just about obtaining a chemical; it's about securing a reliable component that underpins complex synthetic pathways. Adhering to recommended storage conditions, typically at 0-8 °C, is also essential to maintain the compound's integrity and performance over time. The careful consideration of these technical aspects ensures that the potential of Fmoc-Lys(Mtt)-OH is fully realized in all peptide synthesis and chemical research applications.