Fmoc-(S)-3-Amino-4-(4-fluorophenyl)butyric Acid: A Key Intermediate for Novel Therapeutics
The relentless pursuit of novel therapeutics often leads researchers to explore complex molecular structures and advanced synthetic methodologies. Peptide-based drugs represent a significant and growing area within pharmaceutical development, offering high specificity and efficacy. Central to their synthesis are specialized amino acid building blocks that can impart unique properties to the final peptide. NINGBO INNO PHARMCHEM CO.,LTD. is a prominent manufacturer and supplier of such critical intermediates, including Fmoc-(S)-3-Amino-4-(4-fluorophenyl)butyric Acid (CAS: 270062-83-4), a key component for innovation in this field.
Fmoc-(S)-3-Amino-4-(4-fluorophenyl)butyric Acid is a non-natural amino acid derivative that plays a crucial role in the design of peptides with improved pharmacological profiles. The presence of the Fmoc group facilitates its integration into peptide chains using standard solid-phase peptide synthesis techniques, while the 4-(4-fluorophenyl)butyric acid moiety introduces specific characteristics. The fluorine atom, in particular, offers several advantages that are highly valued in medicinal chemistry. Its high electronegativity and the strength of the C-F bond can enhance peptide stability against enzymatic degradation, a common challenge that limits the in vivo efficacy of many peptides. This improved stability means longer circulation times and potentially lower required dosages, making it a more attractive therapeutic option.
Furthermore, the fluorophenyl group can influence the peptide's lipophilicity, which is critical for its absorption, distribution, metabolism, and excretion (ADME) properties. Enhanced lipophilicity can improve cell membrane penetration, leading to better target engagement and overall therapeutic effect. Researchers and procurement managers seeking to purchase advanced peptide precursors will find this compound to be an invaluable addition to their synthetic toolkit. As a dedicated supplier, NINGBO INNO PHARMCHEM CO.,LTD. ensures the availability of this high-purity intermediate to support your drug discovery efforts.
The versatility of Fmoc-(S)-3-Amino-4-(4-fluorophenyl)butyric Acid makes it an ideal building block for creating sophisticated peptide structures, including those designed for targeted drug delivery or interaction with specific biological receptors. Its precise chemical structure and high purity, backed by rigorous quality control, make it a reliable choice for researchers aiming to develop next-generation therapeutics. We are committed to supporting the scientific community by providing access to these essential chemical intermediates. Feel free to contact us to inquire about purchasing options and to learn how we can meet your specific requirements for this and other specialty amino acids.
Perspectives & Insights
Bio Analyst 88
“is a prominent manufacturer and supplier of such critical intermediates, including Fmoc-(S)-3-Amino-4-(4-fluorophenyl)butyric Acid (CAS: 270062-83-4), a key component for innovation in this field.”
Nano Seeker Pro
“Fmoc-(S)-3-Amino-4-(4-fluorophenyl)butyric Acid is a non-natural amino acid derivative that plays a crucial role in the design of peptides with improved pharmacological profiles.”
Data Reader 7
“The presence of the Fmoc group facilitates its integration into peptide chains using standard solid-phase peptide synthesis techniques, while the 4-(4-fluorophenyl)butyric acid moiety introduces specific characteristics.”