NINGBO INNO PHARMCHEM CO.,LTD. is a distinguished provider of specialty chemicals, with Fmoc-Tyr(HPO3Bzl)-OH being a key offering for the research community. This article highlights the critical role of this Fmoc-protected amino acid in the synthesis of phosphopeptides, essential tools for understanding cellular signaling and developing new therapies.

Fmoc-Tyr(HPO3Bzl)-OH, bearing the CAS number 191348-16-0, is a meticulously designed amino acid derivative. It combines the widely used Fmoc protecting group with a benzylphospho moiety attached to the tyrosine side chain. This structural innovation makes it an ideal candidate for researchers aiming to introduce a phosphorylated tyrosine residue into a synthetic peptide sequence using solid-phase peptide synthesis (SPPS) methodologies.

The importance of phosphopeptides in biological research cannot be overstated. Phosphorylation is a ubiquitous post-translational modification that modulates protein activity, localization, and interaction. Synthetic phosphopeptides generated using reagents like Fmoc-Tyr(HPO3Bzl)-OH allow scientists to investigate these regulatory mechanisms with high precision. Researchers frequently inquire about the Fmoc-Tyr(HPO3Bzl)-OH supplier to ensure a dependable source for their experiments. NINGBO INNO PHARMCHEM CO.,LTD. is committed to meeting this need with high-quality products.

The Fmoc/tBu strategy in SPPS is favored for its orthogonality and mild cleavage conditions. The base-labile nature of the Fmoc group allows for its removal by mild bases like piperidine, while the acid-labile tert-butyl (tBu) groups protect the side chains. Fmoc-Tyr(HPO3Bzl)-OH fits seamlessly into this paradigm, enabling the efficient construction of peptides with phosphorylated tyrosine residues. The availability of this compound with a clear Fmoc-Tyr(HPO3Bzl)-OH price from NINGBO INNO PHARMCHEM CO.,LTD. facilitates accessibility for a wide range of research budgets.

Moreover, the benzyl group in the benzylphospho moiety can be removed under various conditions, offering further flexibility in synthetic strategies. This feature enhances the utility of Fmoc-Tyr(HPO3Bzl)-OH in creating diverse phosphorylated peptide structures. For those looking to purchase Fmoc-Tyr(HPO3Bzl)-OH, NINGBO INNO PHARMCHEM CO.,LTD. offers a direct and reliable avenue.

In conclusion, Fmoc-Tyr(HPO3Bzl)-OH (CAS 191348-16-0) is an indispensable building block for researchers in biochemistry, molecular biology, and medicinal chemistry. Its ability to facilitate the synthesis of phosphopeptides is crucial for advancing our understanding of cellular processes and for the development of novel peptide-based therapeutics. NINGBO INNO PHARMCHEM CO.,LTD. is proud to be a key partner in these scientific endeavors.