The choice between gastric-soluble and enteric-soluble film coating powders is a fundamental decision in pharmaceutical tablet formulation. Each type serves distinct purposes, impacting drug release, stability, and therapeutic outcomes. NINGBO INNO PHARMCHEM CO.,LTD., as a specialized pharmaceutical film coating powder manufacturer, offers both types and provides guidance on selecting the optimal powder for your needs.

Gastric Soluble Film Coating Powders: For Immediate Release

Gastric soluble film coating powder is designed for tablets that need to disintegrate and release their active ingredients rapidly in the stomach. These coatings are typically water-soluble and are formulated to break down quickly upon contact with gastric fluids. They are often used to:

  • Mask unpleasant tastes and odors.
  • Protect the tablet core from moisture and light.
  • Improve the visual appeal and ease of swallowing.
  • Provide a smooth, uniform coating for consistent tablet appearance.

If your formulation requires rapid absorption or the API is stable in the stomach, a gastric-soluble coating is generally the preferred choice. When considering the tablet coating powder price, these are often more cost-effective due to simpler formulation requirements.

Enteric Soluble Film Coating Powders: For Targeted Delivery

Enteric soluble film coating powder is formulated to resist dissolution in the acidic environment of the stomach. Instead, it remains intact until it reaches the more alkaline conditions of the small intestine, where it then dissolves to release the API. This delayed-release mechanism is critical for several reasons:

  • Protecting Acid-Sensitive APIs: For drugs that degrade in the stomach's acidic pH, enteric coatings prevent premature breakdown, ensuring the drug reaches the intestine intact.
  • Preventing Gastric Irritation: Some APIs can irritate the stomach lining. Enteric coatings create a barrier, preventing direct contact between the API and the gastric mucosa, thus reducing side effects.
  • Targeted Intestinal Release: For drugs that need to act locally in the intestine or require absorption in that specific segment of the GI tract, enteric coatings ensure precise delivery.

As a leading enteric soluble film coating powder supplier, we ensure our formulations provide reliable pH-dependent dissolution profiles, meeting stringent regulatory requirements.

Factors Influencing Your Choice

When deciding which type of coating powder to buy pharmaceutical film coating powder, consider:

  • API Stability: Is the API degraded by stomach acid?
  • Site of Absorption: Where in the GI tract does the API need to be released?
  • Potential for Gastric Irritation: Does the API cause stomach upset?
  • Desired Release Profile: Do you need immediate or delayed release?

NINGBO INNO PHARMCHEM CO.,LTD. is committed to supporting your formulation development with high-purity, certified film coating powders. Whether you require gastric or enteric solubility, our products are manufactured to the highest standards to ensure the efficacy and safety of your pharmaceutical products. Partner with us for reliable and innovative coating solutions.