Goserelin, a synthetic decapeptide analogue of Gonadotropin-Releasing Hormone (GnRH), is a compound of significant interest in the pharmaceutical industry due to its potent biological activity and role as a key intermediate. Understanding its chemical properties is fundamental to appreciating its pharmaceutical applications, particularly in hormonal therapies. As a dedicated Goserelin manufacturer, we focus on producing this compound with precise specifications to meet industry demands.

Chemically, Goserelin is a peptide composed of ten amino acids. Its molecular formula is C59H84N18O14, with a molecular weight of approximately 1269.41 g/mol. The compound is typically supplied as a white powder, with a reported density of 1.5 g/cm³. Its solubility in water is approximately 20 mg/mL, presenting as a clear, colorless solution. These physical properties are critical for its formulation into various pharmaceutical dosage forms, especially for parenteral administration.

The pharmaceutical significance of Goserelin stems from its function as a Gonadotropin-Releasing Hormone (GnRH) agonist. Naturally occurring GnRH from the hypothalamus stimulates the pituitary gland to release luteinizing hormone (LH) and follicle-stimulating hormone (FSH). These hormones, in turn, signal the gonads (testes in men, ovaries in women) to produce sex hormones like testosterone and estrogen. Goserelin, by mimicking GnRH, initially stimulates this pathway, but due to its modified structure, it leads to a downregulation of GnRH receptors on the pituitary gland.

This downregulation results in a significant reduction in LH and FSH release, consequently leading to a profound decrease in testosterone and estrogen production. This effect is reversible and forms the basis of Goserelin's therapeutic use. For instance, in prostate cancer, where tumor growth is often fueled by androgens, lowering testosterone levels can inhibit cancer progression. Similarly, in breast cancer and certain gynecological conditions driven by estrogen, reducing estrogen is beneficial. This makes Goserelin an essential component in the synthesis of these critical drugs.

For pharmaceutical researchers and formulators looking to buy Goserelin, understanding these chemical and biological properties is vital. The high purity (typically 99%) that we provide as a Goserelin supplier ensures that the synthetic peptide will perform as expected in downstream API manufacturing. The precise chemical structure and low impurity profile are crucial for the safety and efficacy of the final drug product.

The manufacturing process for Goserelin involves complex peptide synthesis, requiring specialized equipment and expertise. As a company with deep experience in fine chemical synthesis, we are well-equipped to produce Goserelin consistently. When you purchase Goserelin from us, you are engaging with a reliable partner that understands the critical nature of this pharmaceutical intermediate. Our commitment to quality and competitive Goserelin prices makes us a preferred choice for many clients.

In summary, Goserelin's chemical structure dictates its potent biological action as a GnRH agonist, making it an indispensable pharmaceutical intermediate. Its role in enabling hormonal therapies for various conditions highlights its profound significance in modern medicine. Partnering with a knowledgeable Goserelin manufacturer like us ensures you receive a product that meets the highest standards.