For procurement managers and R&D scientists in the pharmaceutical and fine chemical industries, sourcing high-quality intermediates is a continuous challenge. (S)-Boc-γ-Iodo-Abu-OMe (CAS: 101650-14-0) is one such compound that frequently appears in synthetic pathways for novel therapeutics and complex organic molecules. Understanding how to source this specific chiral building block efficiently, from identifying reputable manufacturers to comparing prices, is key to successful project execution.

Understanding the Value of (S)-Boc-γ-Iodo-Abu-OMe

(S)-Boc-γ-Iodo-Abu-OMe is prized for its specific molecular structure. It features a tert-butyloxycarbonyl (Boc) protected amine group, which is standard for controlled synthetic reactions, and a reactive iodine atom at the gamma position. This iodine atom acts as a leaving group, making it ideal for various coupling and substitution reactions that are fundamental in constructing more complex organic frameworks, including peptides and active pharmaceutical ingredients (APIs).

The 'S' designation signifies its specific stereochemistry. In drug development, chirality is often critical; the biological activity of a molecule can drastically differ based on its spatial arrangement. Therefore, obtaining (S)-Boc-γ-Iodo-Abu-OMe with high enantiomeric purity is non-negotiable for many applications. This makes it a sought-after pharmaceutical intermediate and a critical component for any research team focused on stereoselective synthesis.

Key Considerations When Purchasing

When you need to buy (S)-Boc-γ-Iodo-Abu-OMe, several factors should guide your purchasing decision:

  • Manufacturer Reputation: The quality of your final product directly depends on the quality of your starting materials. Always look for established manufacturers with a proven track record in producing fine chemicals and chiral intermediates. Companies specializing in amino acid derivatives and peptide chemistry are often the best bet.
  • Product Specifications: Beyond the CAS number, check for detailed specifications such as purity (often >95% or >98%), appearance (typically white to off-white solid), and chiral purity (enantiomeric excess). Suppliers should readily provide a Certificate of Analysis (CoA) detailing these parameters.
  • Pricing and Quotation: Prices for such intermediates can vary significantly based on purity, quantity, and supplier. It is advisable to request quotations from multiple qualified suppliers. Consider not just the per-gram price but also any bulk discounts or shipping costs. For example, if you are a procurement manager looking to secure a reliable supply for ongoing manufacturing, understanding the price structure for larger quantities is essential.
  • Availability and Lead Times: For time-sensitive projects, inquire about stock availability and estimated delivery times. A responsive supplier will be transparent about lead times, especially for international shipments.

Navigating the Market for (S)-Boc-γ-Iodo-Abu-OMe

The global market offers numerous suppliers for (S)-Boc-γ-Iodo-Abu-OMe, with many based in China, known for its robust chemical manufacturing sector. When sourcing, especially for bulk purchases, working with manufacturers who can provide consistent quality and competitive pricing is paramount. Consider suppliers who also offer related compounds or custom synthesis services, as this can streamline your procurement process.

In summary, a strategic approach to purchasing (S)-Boc-γ-Iodo-Abu-OMe involves thorough research into potential suppliers, a clear understanding of product specifications, and careful price comparison. By focusing on quality and reliability, you can ensure your synthetic endeavors are built on a solid foundation.