For research and development in the pharmaceutical and fine chemical sectors, access to high-quality, specialized chemical intermediates is non-negotiable. 4-(TrifluoroMethoxy)phenyl isothiocyanate, identified by its CAS number 64285-95-6, is one such compound that has garnered significant interest. Its unique chemical structure makes it a valuable precursor for synthesizing a wide array of complex organic molecules. This guide aims to provide procurement managers and research scientists with the essential information needed to effectively buy this intermediate, focusing on its properties, applications, and reliable sourcing strategies.

Key Properties and Applications of 4-(Trifluoromethoxy)phenyl Isothiocyanate

With a molecular formula of C8H4F3NOS and a molecular weight of 219.18, 4-(TrifluoroMethoxy)phenyl isothiocyanate is characterized by a high purity, typically 99.0%min. This purity level is critical for its primary application as a pharmaceutical intermediate. The trifluoromethoxy group imparts distinct electronic and lipophilic properties, which can significantly influence the efficacy and pharmacokinetic profile of the final drug product. The isothiocyanate functional group, meanwhile, offers versatile reactivity, allowing it to participate in various coupling and cyclization reactions to form essential motifs like thioureas and heterocycles. These make it indispensable for medicinal chemists designing novel therapeutic agents.

Sourcing Strategies for Procurement Professionals

When seeking to buy 4-(Trifluoromethoxy)phenyl isothiocyanate, procurement professionals should consider several factors to ensure a successful transaction:

  • Manufacturer Reliability: Directly engaging with manufacturers, especially those based in China with a strong track record like NINGBO INNO PHARMCHEM CO.,LTD., often provides the best combination of quality, price, and supply chain stability.
  • Product Specifications: Always verify the assay and purity levels, ensuring they meet the stringent requirements of your R&D or manufacturing processes. A minimum assay of 99.0% is a common standard for this intermediate.
  • Packaging and Delivery: Understand the available packaging options (e.g., 25kg/drum) and inquire about delivery timelines and logistical support.
  • Technical Data: Requesting a Certificate of Analysis (CoA) and Material Safety Data Sheet (MSDS) is standard practice and essential for compliance and safety.

The ability to procure this intermediate reliably and cost-effectively is crucial for advancing drug discovery projects. By focusing on quality, supply chain security, and understanding the chemical's specific applications, R&D teams can secure the necessary materials to drive innovation. Therefore, actively seeking out experienced suppliers for CAS 64285-95-6 is a strategic imperative for any organization engaged in advanced chemical synthesis and pharmaceutical development.