Methyl sinapate, chemically known as Methyl 3-(4-hydroxy-3,5-dimethoxyphenyl)propenoate (CAS 20733-94-2), is emerging as a compound of significant interest within the pharmaceutical and cosmetic industries. Its unique chemical structure, derived from sinapic acid, bestows upon it valuable properties, including notable UV absorption and antioxidant capabilities. For procurement managers and R&D scientists seeking high-quality pharmaceutical intermediates, understanding the nuances of this compound is key to unlocking innovative product development.

Synthesis and Production: The Manufacturer's Advantage

The production of Methyl sinapate typically involves established organic synthesis routes such as the Knoevenagel-Doebner condensation, reacting syringaldehyde with malonic acid monomethyl ester, or direct methylation of sinapic acid. Manufacturers like NINGBO INNO PHARMCHEM CO.,LTD. focus on optimizing these processes to ensure high purity (often >99%) and consistent yield. For businesses looking to buy pharmaceutical intermediates, sourcing directly from a reputable manufacturer in China offers significant advantages in terms of cost-effectiveness and supply chain reliability. When inquiring about Methyl sinapate, specifying CAS 20733-94-2 will ensure accurate product identification.

Bioactive Properties: From UV Protection to Antioxidant Power

Research highlights the compound's efficacy in photoprotection, making it a compelling ingredient for developing natural sunscreen agents. Its ability to absorb UV radiation effectively and dissipate energy contributes to its protective function against cellular damage. Furthermore, Methyl sinapate exhibits significant antioxidant properties, crucial for combating oxidative stress in cosmetic and pharmaceutical formulations. This dual functionality makes it a versatile component for products aimed at skin health and anti-aging. Its potential applications extend to anti-inflammatory and antimicrobial activities, as suggested by studies on its analogues.

Analytical Characterization and Quality Assurance

To ensure the highest quality for research and manufacturing, comprehensive analytical data is paramount. Techniques such as Nuclear Magnetic Resonance (NMR) spectroscopy provide detailed structural elucidation, while Mass Spectrometry (MS) confirms the molecular weight and fragmentation patterns. High-Performance Liquid Chromatography (HPLC) is indispensable for assessing purity and quantifying the compound, ensuring that batches meet the strict specifications required for pharmaceutical intermediates. Manufacturers should be prepared to provide detailed certificates of analysis upon inquiry.

Procurement and Supply Chain Considerations

For companies looking to purchase Methyl sinapate, partnering with an established supplier is crucial. Understanding the market for pharmaceutical intermediates in China reveals that reliable manufacturers offer competitive pricing and a stable supply chain, mitigating risks associated with material availability. When seeking a quote, inquiries should be specific, referencing the CAS number 20733-94-2 and the required purity. Bulk purchase inquiries are welcome, ensuring that larger-scale manufacturing needs can be met efficiently.

In conclusion, Methyl 3-(4-hydroxy-3,5-dimethoxyphenyl)propenoate (CAS 20733-94-2) represents a valuable asset for pharmaceutical and cosmetic R&D. Its well-documented properties and the availability from reliable manufacturers position it as a key ingredient for future innovations.