HBTU (94790-37-1): Your Go-To Coupling Reagent for Peptide Manufacturing
In the dynamic field of pharmaceutical development and fine chemical manufacturing, the efficiency and purity of synthesized compounds are non-negotiable. For peptide synthesis, a critical process in creating life-saving drugs and advanced biomaterials, the choice of coupling reagent is paramount. HBTU (CAS 94790-37-1) has emerged as a cornerstone reagent, celebrated for its effectiveness and reliability. As a dedicated manufacturer and supplier based in China, we understand the demands of the B2B market and are committed to providing high-quality HBTU to meet these needs.
HBTU, scientifically known as 2-(1H-benzotriazol-1-yl)-1,1,3,3-tetramethyluronium hexafluorophosphate, plays a pivotal role in facilitating amide bond formation. Its primary application lies in solid-phase peptide synthesis (SPPS), a technique widely adopted by researchers and pharmaceutical companies for its automation and efficiency. The reagent activates the carboxyl group of an amino acid, making it susceptible to nucleophilic attack by the amino group of another amino acid or peptide chain. This straightforward activation mechanism contributes to its popularity.
One of the most sought-after attributes of HBTU is its ability to perform couplings with minimal racemization. Racemization, the loss of stereochemical integrity during peptide synthesis, can significantly impact the biological activity and safety profile of the final peptide product. HBTU's chemical structure and reaction kinetics help to suppress this side reaction, ensuring that the synthesized peptides retain their desired chirality. This is a crucial consideration for any procurement manager or R&D scientist focused on producing high-quality pharmaceutical intermediates.
The commercial availability of HBTU with a high assay, typically 99%, further solidifies its position as a superior choice. When you decide to buy HBTU, seeking a supplier that guarantees this level of purity is essential for predictable outcomes in your synthesis. Our manufacturing process adheres to strict quality controls, ensuring that you receive a product that performs consistently. This reliability is what distinguishes reputable chemical suppliers in the global market.
Sourcing chemical reagents from China has become a strategic advantage for many businesses, particularly for bulk requirements. As a direct manufacturer, we offer HBTU at competitive prices, enabling cost-effective production scaling. Our logistics and export capabilities are designed to serve global clients efficiently. For companies looking to secure a stable supply of this critical reagent, understanding our price structure and delivery options is vital.
In conclusion, HBTU (CAS 94790-37-1) is an indispensable reagent for modern peptide synthesis. Its high purity, low racemization characteristics, and overall efficiency make it a valuable asset for pharmaceutical research and manufacturing. We are proud to be a reliable supplier of HBTU, offering exceptional quality and value to businesses worldwide. Engage with us to learn more about how our HBTU can support your peptide synthesis requirements and to discuss bulk purchasing options.
Perspectives & Insights
Core Pioneer 24
“This reliability is what distinguishes reputable chemical suppliers in the global market.”
Silicon Explorer X
“Sourcing chemical reagents from China has become a strategic advantage for many businesses, particularly for bulk requirements.”
Quantum Catalyst AI
“As a direct manufacturer, we offer HBTU at competitive prices, enabling cost-effective production scaling.”