In the competitive landscape of pharmaceutical research and development, access to high-quality chemical intermediates is crucial for success. Tert-butyl 4,7-diazaspiro[2.5]octane-4-carboxylate is a prime example of such an intermediate, offering unique structural features that are highly valued by synthetic chemists. This article highlights the importance of this compound, its applications, and provides guidance for procurement professionals on how to source it effectively from reliable manufacturers.

The Chemical Profile of tert-Butyl 4,7-Diazaspiro[2.5]octane-4-carboxylate

Tert-butyl 4,7-diazaspiro[2.5]octane-4-carboxylate (CAS: 674792-08-6) is characterized by its spirocyclic structure, featuring a diazaspirene core. Its molecular formula is C11H20N2O2, with a molecular weight of 212.29 g/mol. Typically appearing as an off-white to light yellow solid, it possesses a purity level of 95% or greater, with many suppliers offering material at 97% purity. The compound's physical properties, such as its boiling point (301.3 °C at 760 mmHg) and flash point (136 °C), are important considerations for handling and storage in laboratory settings. As a building block, its value stems from the ability to introduce a conformationally constrained diamine moiety into larger organic molecules.

Applications in Pharmaceutical R&D

The primary utility of tert-butyl 4,7-diazaspiro[2.5]octane-4-carboxylate lies in its application as a versatile intermediate in the synthesis of active pharmaceutical ingredients (APIs). Its spirocyclic nature can impart desirable pharmacokinetic properties and enhance the potency and selectivity of drug candidates. Medicinal chemists often employ this building block in the development of novel therapeutics targeting a wide array of diseases. For procurement managers, understanding the demand for such specialized intermediates is key to maintaining an efficient R&D supply chain.

Why Choose a Chinese Manufacturer?

When looking to buy tert-butyl 4,7-diazaspiro[2.5]octane-4-carboxylate, partnering with a reputable Chinese chemical manufacturer offers significant advantages. China has a robust chemical manufacturing infrastructure, capable of producing complex intermediates at scale and often at a more competitive price point compared to Western suppliers. For researchers requiring this compound, identifying a trustworthy supplier is paramount. Key factors to consider include:

  • Product Purity and Consistency: Ensure the supplier provides a detailed CoA confirming purity levels.
  • Production Capacity: For larger projects, confirm the supplier can meet volume demands.
  • Regulatory Compliance: Verify that the supplier adheres to international quality and safety standards.
  • Logistics and Support: Look for suppliers with established export processes and responsive customer service.

Securing a reliable source for tert-butyl 4,7-diazaspiro[2.5]octane-4-carboxylate from a trusted Chinese supplier can significantly streamline your drug discovery efforts. Purchase this essential building block to unlock new avenues in your research.