In the realm of chemical synthesis, the quality and specificity of intermediates are fundamental to the success of any project. D-2-Thienylalanine, identified by its CAS number 62561-76-6, is a specialized amino acid derivative that serves as a valuable intermediate in various chemical syntheses. Its unique structure, featuring a thiophene ring and a chiral center, makes it a sought-after compound for researchers and manufacturers across different industries. This article highlights the importance of high-quality D-2-Thienylalanine and guides on how to procure it effectively.

Understanding the Chemical Properties of D-2-Thienylalanine

D-2-Thienylalanine is an unnatural amino acid, meaning it is not one of the 20 standard amino acids found in proteins. Its chemical structure consists of an alanine backbone where a hydrogen atom on the beta-carbon is replaced by a 2-thienyl group. The 'D' prefix denotes its specific stereochemistry at the alpha-carbon. This chirality is often crucial for its application in stereoselective synthesis, particularly in the pharmaceutical industry where enantiomeric purity is vital for drug efficacy and safety. Typically supplied as a white to off-white solid, its physical state and purity are key specifications that manufacturers must adhere to.

The Role of D-2-Thienylalanine as a Chemical Intermediate

As a chemical intermediate, D-2-Thienylalanine acts as a building block for constructing more complex molecules. Its amino and carboxyl groups can participate in standard peptide coupling reactions, while the thiophene ring offers a site for further functionalization or contributes unique electronic and steric properties to the final product. This versatility makes it useful in the synthesis of:

  • Pharmaceuticals: Particularly in the development of novel drugs targeting neurological conditions, and in peptide-based therapeutics.
  • Agrochemicals: As a potential building block for specialized pesticides or plant growth regulators.
  • Specialty Materials: Where the thiophene moiety can impart desirable electronic or optical properties.

The demand for high-purity D-2-Thienylalanine is driven by the stringent requirements of these applications, where impurities can lead to unwanted side reactions or compromised product performance.

Finding Reliable Suppliers and Manufacturers

When you need to buy D-2-Thienylalanine, selecting a reliable manufacturer is paramount. Look for suppliers that explicitly state their commitment to quality control and provide detailed product specifications, including CAS number (62561-76-6), purity (e.g., ≥98% or ≥99% HPLC), and molecular weight. Manufacturers based in China are often excellent sources for such specialized intermediates, offering competitive pricing and robust production capacities. It is always advisable to request a quote and compare offerings from different vendors to ensure you receive the best value and quality for your chemical synthesis needs.

Conclusion

D-2-Thienylalanine (CAS 62561-76-6) is a critical intermediate for advanced chemical synthesis. Its precise stereochemistry and unique thiophene functionality make it indispensable for many applications. By partnering with reputable manufacturers and ensuring the specified quality standards are met, researchers and chemical producers can confidently integrate this valuable building block into their processes, driving innovation and achieving successful synthesis outcomes.