The Historical Significance and Modern Use of Piperazine as an Anthelmintic
Piperazine, identified by its CAS number 110-85-0, boasts a significant history in medicine, primarily for its efficacy as an anthelmintic. This organic compound, a cyclic diamine, has been instrumental in treating parasitic worm infections, most notably ascariasis (roundworm) and enterobiasis (pinworm). Its mechanism of action is well-understood: Piperazine acts as a GABA agonist on helminthic neuromuscular junctions, causing hyperpolarization and paralysis of the parasites. Once paralyzed, the worms are easily expelled from the host's digestive system.
The widespread use of Piperazine as a deworming agent led to its extensive production and marketing by pharmaceutical companies. While newer, broader-spectrum anthelmintics have emerged, Piperazine remains a valuable and cost-effective option in certain veterinary and human health contexts. For manufacturers of anthelmintic drugs, securing a reliable supply of high-purity Piperazine is a critical business imperative.
NINGBO INNO PHARMCHEM CO.,LTD., as a premier manufacturer and supplier of Piperazine from China, plays a vital role in meeting this demand. Their commitment to producing Piperazine with exceptional purity ensures that it is suitable for pharmaceutical formulations. For businesses looking to buy Piperazine for anthelmintic production, partnering with a trusted supplier like NINGBO INNO PHARMCHEM guarantees product quality and consistency, which are non-negotiable in the pharmaceutical industry.
Beyond its direct anthelmintic use, Piperazine is also a key intermediate in the synthesis of other complex pharmaceutical compounds. Its chemical structure lends itself to derivatization, leading to a range of pharmacologically active substances. This dual utility – as an active ingredient and as a synthetic precursor – underscores the enduring importance of Piperazine in the broader chemical and pharmaceutical landscape.
For procurement managers and formulators in the pharmaceutical and veterinary sectors, understanding the supply chain for essential raw materials like Piperazine is crucial. NINGBO INNO PHARMCHEM CO.,LTD. offers a robust solution, providing global access to high-quality Piperazine at competitive prices. Their expertise in manufacturing and export makes them an ideal partner for companies that need to source this historically significant and still relevant chemical compound.
Perspectives & Insights
Bio Analyst 88
“offers a robust solution, providing global access to high-quality Piperazine at competitive prices.”
Nano Seeker Pro
“Their expertise in manufacturing and export makes them an ideal partner for companies that need to source this historically significant and still relevant chemical compound.”
Data Reader 7
“Piperazine, identified by its CAS number 110-85-0, boasts a significant history in medicine, primarily for its efficacy as an anthelmintic.”