Hyodeoxycholic Acid (HDCA), identified by its CAS number 83-49-8, is a compound of significant interest across pharmaceutical research and development. As a secondary bile acid, its unique molecular structure and properties lend themselves to crucial applications, most notably as a precursor in steroid synthesis and as a chemical chaperone in various biological studies. For R&D scientists and procurement professionals looking to purchase this compound, understanding its applications and sourcing reliable suppliers is key.

Role in Steroid Synthesis

Historically, Hyodeoxycholic Acid extracted from animal bile served as a vital starting material for the synthesis of steroids, including hormones like progesterone. While advancements in total synthesis have provided alternative routes, HDCA remains a significant intermediate due to its specific stereochemistry, which can simplify certain synthetic pathways. Manufacturers offering Hyodeoxycholic Acid often highlight its utility in this area, emphasizing the purity levels required for pharmaceutical synthesis. Procurement managers seeking to buy this compound for steroid production should look for suppliers who can guarantee high purity (often >99%) and a consistent supply, backed by certifications like GMP.

Hyodeoxycholic Acid as a Chemical Chaperone

Beyond its role in synthesis, Hyodeoxycholic Acid functions as a chemical chaperone. This means it assists in the proper folding and stabilization of proteins, preventing misfolding and aggregation. This property is invaluable in laboratory settings for maintaining protein structure and function, which is critical for research in molecular biology, biochemistry, and drug discovery. Scientists often seek to buy Hyodeoxycholic Acid to support experiments requiring stable protein conformations or to study protein-ligand interactions. Suppliers who provide detailed technical data, including solubility and stability information, are particularly valuable to researchers.

Sourcing Hyodeoxycholic Acid

When it comes to sourcing Hyodeoxycholic Acid, particularly from a competitive market like China, several points are crucial. Buyers should prioritize suppliers that can demonstrate:

  • High Purity: A minimum of 99% purity is typically required for both synthesis and research applications.
  • Quality Certifications: ISO and GMP certifications indicate a commitment to quality standards.
  • Reliable Supply: Manufacturers with substantial production capacity ensure product availability for ongoing projects.
  • Technical Support: Suppliers who can provide detailed product information and assist with technical inquiries are highly beneficial.

By understanding the critical applications of Hyodeoxycholic Acid and focusing on reputable manufacturers and suppliers, research institutions and pharmaceutical companies can ensure they procure a high-quality intermediate that supports their critical scientific and manufacturing endeavors.