The field of advanced chemical synthesis is constantly evolving, driven by the need for more efficient, selective, and sustainable methods to create complex molecules. Organoboron compounds, particularly boronic acids, have risen to prominence as indispensable tools in this evolution, largely due to their pivotal role in palladium-catalyzed cross-coupling reactions. Among these, 4-Butylphenylboronic Acid (CAS: 145240-28-4) stands out for its versatile applications and unique chemical properties.

4-Butylphenylboronic Acid: A Catalyst for Innovation

4-Butylphenylboronic Acid is an aromatic boronic acid derivative featuring a butyl substituent. This seemingly simple modification confers significant advantages, most notably enhanced solubility in a wider range of organic solvents. This improved solubility translates to more efficient reaction kinetics and easier handling in synthesis, making it a preferred reagent for chemists. Its primary application is in the Suzuki-Miyaura cross-coupling reaction, a powerful method for forming carbon-carbon bonds. In this reaction, 4-Butylphenylboronic Acid acts as a nucleophilic coupling partner, reacting with aryl or vinyl halides under palladium catalysis to generate complex biaryl systems and other valuable organic structures.

The impact of 4-Butylphenylboronic Acid is felt across several key scientific domains:

  • Drug Discovery and Development: In the pharmaceutical sector, this compound serves as a critical intermediate for synthesizing active pharmaceutical ingredients (APIs) and novel drug candidates. Its ability to precisely assemble molecular frameworks is essential for creating molecules with targeted therapeutic effects. Researchers rely on its consistent quality and availability to drive their discovery pipelines forward.
  • Material Science: The development of advanced materials, such as functional polymers, organic semiconductors, and liquid crystals, often relies on sophisticated synthetic routes. 4-Butylphenylboronic Acid is instrumental in creating these materials, allowing for the precise assembly of monomers and the fine-tuning of material properties.
  • General Organic Synthesis: Beyond these specialized fields, it is a staple reagent in academic research and custom synthesis, facilitating the construction of intricate organic molecules for a variety of studies.

Sourcing High-Quality 4-Butylphenylboronic Acid

For organizations aiming to leverage the capabilities of 4-Butylphenylboronic Acid, sourcing from a reputable manufacturer is crucial. Key considerations when looking to buy include:

  • Product Purity: Ensuring high purity (e.g., ≥98% by HPLC) is vital for reproducibility and efficiency in complex synthetic steps.
  • Manufacturing Expertise: Partnering with experienced manufacturers, particularly those in China with established chemical production capabilities, ensures consistent quality and reliable supply.
  • Competitive Pricing: Access to cost-effective sourcing is essential for managing project budgets and scaling up production.
  • Customer Support: Availability of technical data, safety information, and responsive customer service facilitates smooth integration into research and production workflows.

As a dedicated manufacturer and supplier, we are committed to providing 4-Butylphenylboronic Acid that meets these stringent requirements. Our focus on quality, competitive pricing, and reliable global supply ensures that our clients have access to the critical chemical building blocks they need to drive innovation. By choosing a trusted source, you can confidently advance your projects in advanced chemical synthesis.

In essence, 4-Butylphenylboronic Acid is a testament to the power of well-designed chemical intermediates in shaping modern scientific and technological progress.