The pharmaceutical industry's relentless pursuit of novel and effective therapies hinges on the availability of high-quality raw materials and intermediates. Among these, heterocyclic compounds often serve as foundational structures for a vast array of drugs. 2-Bromobenzofuran (CAS: 54008-77-4) stands out as a key intermediate, vital for the synthesis of many pharmaceutical ingredients. For procurement managers and formulation scientists, understanding the sourcing and application of this compound is crucial.

2-Bromobenzofuran: A Cornerstone for Pharmaceutical Synthesis

2-Bromobenzofuran is a valuable heterocyclic organic compound, characterized by its benzofuran ring system with a bromine atom at the 2-position. Typically supplied as a liquid with a purity of 97% or higher, its molecular formula is C8H5BrO, and its molecular weight is 197.03 g/mol. This chemical structure lends itself to a variety of synthetic manipulations essential for creating Active Pharmaceutical Ingredients (APIs).

As a pharmaceutical raw material, 2-Bromobenzofuran is often employed in:

  • Drug Discovery and Development: Its heterocyclic scaffold can be incorporated into new molecular entities (NMEs) being investigated for various therapeutic properties.
  • Synthesis of Existing APIs: It may serve as a key building block in established multi-step synthesis routes for existing medications.
  • Medicinal Chemistry Research: The compound's reactive bromine atom facilitates diverse coupling reactions, allowing chemists to modify and explore structure-activity relationships (SAR).

The ability to reliably buy 2-Bromobenzofuran with guaranteed purity is critical for ensuring the efficacy and safety of the final pharmaceutical product.

Sourcing High-Quality 2-Bromobenzofuran: A B2B Perspective

For businesses needing to procure 2-Bromobenzofuran, partnering with a reputable manufacturer or supplier is paramount. When searching for this vital intermediate, consider the following:

  • Supplier Reliability and Origin: Look for established chemical companies, especially those in China, that have a strong track record in manufacturing and exporting fine chemicals and pharmaceutical intermediates.
  • Product Specifications and Documentation: Always verify that the supplier provides detailed specifications, including purity (e.g., 97% min.) and offers a Certificate of Analysis (CoA) for each batch. Access to Safety Data Sheets (SDS) is also essential for safe handling.
  • Competitive Pricing: Obtaining quotes from multiple suppliers can help ensure you get the best price for 2-Bromobenzofuran. However, quality and reliability should not be compromised for cost savings.
  • Customization and Support: For specific project needs, inquire about custom synthesis or packaging options. Responsive customer support is also a key indicator of a good supplier.

When you need to purchase 2-Bromobenzofuran, online searches using terms like 'pharmaceutical intermediate supplier China' or 'CAS 54008-77-4 for sale' will be beneficial. Many platforms allow direct comparison of product offerings and supplier capabilities.

In summary, 2-Bromobenzofuran is an indispensable intermediate in the pharmaceutical industry. By carefully selecting a qualified manufacturer or supplier, B2B buyers can ensure the procurement of high-quality raw materials, which is fundamental for successful drug development and manufacturing. Prioritizing product integrity and supplier reliability will ultimately contribute to the delivery of safe and effective medicines.