For research and development scientists, understanding the detailed chemical profile of a compound is critical for successful application and synthesis. Indole-2-carboxaldehyde (CAS: 19005-93-7), a key heterocyclic compound, offers a fascinating combination of structural features and reactivity that make it invaluable in various chemical endeavors. As a dedicated chemical manufacturer, we are committed to providing precise information about our products to facilitate your work.

The molecular formula of Indole-2-carboxaldehyde is C9H7NO, with a molecular weight of 145.16 g/mol. Its structure features an indole ring fused with an aldehyde group at the second position. This arrangement imbues the molecule with unique chemical properties. Key physical characteristics often reported include its melting point, typically around 138-142 °C, and its appearance as an off-white to light brown solid. These parameters are crucial for handling, storage, and process design. A minimum purity of 96.5% is commonly specified for high-grade material, ensuring its suitability for demanding synthetic routes.

The aldehyde functional group (-CHO) attached to the electron-rich indole system is the primary site of reactivity. This makes Indole-2-carboxaldehyde an excellent electrophile, readily participating in a multitude of organic reactions. Common transformations include:

  • Nucleophilic Addition Reactions: The aldehyde group can react with nucleophiles such as Grignard reagents, organolithium compounds, and amines, leading to the formation of alcohols, imines, and other derivatives.
  • Condensation Reactions: It undergoes condensation with active methylene compounds (e.g., Knoevenagel condensation) and amines to form various heterocyclic systems and Schiff bases.
  • Oxidation and Reduction Reactions: The aldehyde can be oxidized to a carboxylic acid or reduced to an alcohol, providing access to different functional groups.
  • Wittig and Related Olefination Reactions: These reactions allow for the introduction of carbon-carbon double bonds, extending the molecular framework.

These synthetic pathways are fundamental for chemists aiming to synthesize complex molecules. For instance, the ability to readily functionalize the aldehyde group makes Indole-2-carboxaldehyde a prime candidate for building diverse pharmaceutical intermediates, advanced dyes, and components for electronic materials. When you purchase Indole-2-carboxaldehyde, you are acquiring a versatile synthon ready for complex molecular construction.

As a trusted supplier of Indole-2-carboxaldehyde in China, we ensure that our product's quality is consistently maintained. We understand that precise chemical properties and high purity are non-negotiable for R&D scientists. Therefore, we provide comprehensive technical data and support to assist you in leveraging the full synthetic potential of this important chemical.

In summary, Indole-2-carboxaldehyde is a compound defined by its accessible aldehyde functionality and the inherent properties of its indole core. Its rich reactivity profile makes it a cornerstone for innovation in organic synthesis, pharmaceutical research, and material science. We encourage you to explore its potential by acquiring this high-quality chemical from a reliable source.