For researchers and development scientists, sourcing high-quality chemical building blocks is a fundamental aspect of pioneering new discoveries. 1-Bromo-2-chloro-4-(trifluoromethyl)benzene, also identified by its CAS number 402-04-0 and often referred to by its systematic name 4-Bromo-3-chlorobenzotrifluoride, is a critical intermediate for various research applications, particularly in organic synthesis. When you need to buy this compound for your R&D projects, selecting the right supplier is key to ensuring the integrity and reproducibility of your experiments.

The Role of 1-Bromo-2-chloro-4-(trifluoromethyl)benzene in R&D

This trifluoromethylbenzene derivative offers a unique combination of reactive sites and structural features that are highly prized in synthetic chemistry. Its utility spans across multiple research areas:

  • Fine Chemical Synthesis: It serves as a foundational component for constructing more complex organic molecules, often acting as a starting material for novel compounds with specific electronic or physical properties.
  • Medicinal Chemistry: Researchers developing new drug candidates frequently utilize fluorinated aromatic compounds. The trifluoromethyl group can improve metabolic stability, lipophilicity, and binding affinity, making this intermediate valuable in the early stages of drug discovery.
  • Material Science: The specific chemical properties imparted by the halogen and trifluoromethyl substituents can be beneficial in the synthesis of advanced materials, polymers, or specialty chemicals.

Criteria for Selecting R&D Suppliers

When scouting for a supplier of 1-Bromo-2-chloro-4-(trifluoromethyl)benzene for R&D purposes, consider these essential criteria:

  1. Small Batch Availability: R&D often requires smaller quantities, ranging from grams to kilograms. Suppliers who offer flexible order sizes and readily available stock for these amounts are ideal.
  2. Purity and Analytical Data: While bulk users might tolerate slightly lower purities, R&D demands high purity (e.g., ≥98.0%) and detailed analytical reports (COA, NMR, GC-MS) to validate experimental results. The ability to provide this data readily is a sign of a competent supplier.
  3. Technical Support: For R&D scientists, having access to technical support from the supplier can be invaluable. A supplier knowledgeable about their products can offer insights into handling, storage, and potential applications.
  4. Delivery Speed: Research timelines can be tight. Suppliers with efficient shipping and logistics, particularly those capable of express delivery, are highly preferred.
  5. Reputation and Reviews: Look for suppliers with positive feedback from other research institutions or companies. This can be found through industry forums, chemical marketplaces, or direct recommendations.

Sourcing from China: Opportunities and Considerations

Many manufacturers in China offer competitive pricing and a wide range of intermediates suitable for R&D. When choosing a Chinese supplier for 1-Bromo-2-chloro-4-(trifluoromethyl)benzene, it’s advisable to:

  • Prioritize suppliers who clearly list their product specifications and analytical data online.
  • Request samples to confirm quality and suitability for your specific research before committing to larger R&D quantities.
  • Ensure they have experience exporting to your region and understand international shipping regulations.

Ultimately, building a relationship with a reliable supplier for your R&D needs is about more than just the chemical itself. It's about partnership, ensuring you have the materials you need, when you need them, with the quality required to drive your scientific objectives forward. If you are looking to buy this essential intermediate, focusing on these supplier attributes will lead to more successful research outcomes.