NINGBO INNO PHARMCHEM CO.,LTD. is pleased to offer insights into 4-Bromo-2-methyl-6-nitroaniline (CAS: 77811-44-0), a compound of considerable interest in chemical and pharmaceutical research. This article delves into its core chemical properties and highlights its diverse applications, particularly as a pharmaceutical intermediate.

Characterized by its orange solid appearance, 4-Bromo-2-methyl-6-nitroaniline exhibits a melting point typically ranging from 143-147°C. Its chemical formula is C7H7BrN2O2, with a molecular weight of approximately 231.05 g/mol. The compound is sparingly soluble in water but shows good solubility in hot methanol, a property often leveraged during synthesis and purification processes. The presence of the nitro group and bromine atom influences its reactivity, making it a valuable reactant in various organic transformations.

The primary utility of 4-Bromo-2-methyl-6-nitroaniline lies in its role as a precursor for advanced molecular structures. It is extensively used in the design and synthesis of CK2 inhibitors. CK2 (Casein Kinase 2) is a protein kinase that plays a crucial role in regulating cell growth and survival, and its aberrant activity is implicated in several diseases, including cancer. The development of selective CK2 inhibitors is a significant area of pharmaceutical research, and this compound serves as a critical starting material. Understanding efficient 4-Bromo-2-methyl-6-nitroaniline synthesis is key for researchers in this field.

Furthermore, this intermediate is employed in the docking studies of novel telmisartan-glitazone hybrid analogs. These hybrids are being investigated for their potential in treating metabolic syndrome, a cluster of conditions that increase the risk of heart disease, stroke, and diabetes. The structural integrity and precise 4-Bromo-2-methyl-6-nitroaniline synthesis provided by NINGBO INNO PHARMCHEM CO.,LTD. ensure that these complex pharmaceutical molecules can be reliably constructed.

As a reputable manufacturer and supplier in China, we are committed to delivering premium quality chemical intermediates. Our focus on rigorous quality control ensures that researchers and developers receive a product that meets exact specifications, facilitating reproducible and successful experimental outcomes. If you are seeking to purchase or buy 4-Bromo-2-methyl-6-nitroaniline for your research needs, NINGBO INNO PHARMCHEM CO.,LTD. offers a dependable source for this essential chemical.