The study of iron overload disorders is a complex but vital area of medical research. Central to many investigations is the compound Deferiprone, identified by CAS number 30652-11-0. For scientists and procurement specialists, understanding this chemical's properties and how to source it is key to advancing research in this field. This article explores the significance of Deferiprone and guides potential buyers on how to buy it from reputable sources.

Deferiprone: An Essential Iron Chelator

Deferiprone is a synthetic hydroxypyridin-4-one derivative that functions as a potent iron chelator. Its molecular formula, C7H9NO2, describes a molecule specifically designed to bind with ferric ions (Fe³⁺). This binding forms a stable, neutral complex that can then be excreted from the body, thereby reducing excess iron accumulation. Its efficacy in chelating iron makes it a valuable tool in preclinical research aimed at understanding and treating conditions characterized by iron overload, such as thalassemia major, sickle cell disease, and other inherited blood disorders.

Research Applications and Purity Requirements

In the scientific community, Deferiprone is sought after for its application in various research settings. Researchers investigate its impact on cellular iron levels, oxidative stress, and organ damage associated with iron toxicity. For these studies, high purity is non-negotiable. A minimum assay of ≥99% is typically specified to ensure that experimental results are accurate and reproducible, without interference from impurities. When seeking to purchase Deferiprone for research, always verify the purity standards offered by the manufacturer or supplier.

Sourcing Deferiprone: What Buyers Need to Know

Procuring Deferiprone for laboratory or pharmaceutical development requires careful consideration:

  • Supplier Verification: It is crucial to identify trusted suppliers and manufacturers. Look for companies with a proven track record in supplying fine chemicals and pharmaceutical intermediates. Online product listings often provide CAS numbers, molecular formulas, and purity specifications.
  • Requesting a Quote: To obtain accurate price information, especially for research quantities or bulk orders, submitting an inquiry with your specific requirements is essential. A prompt response with a detailed quote indicates a responsive supplier.
  • Certificate of Analysis (CoA): Always request a CoA for any batch of Deferiprone purchased. This document confirms the product's identity, purity, and other critical parameters, ensuring it meets your research or production needs.
  • Supply Chain Stability: For ongoing research projects or drug development pipelines, ensuring a consistent supply is vital. Discuss lead times and inventory availability with your chosen supplier.

The Role of Chinese Manufacturers

The global chemical market benefits significantly from manufacturers in China, which are renowned for producing high-quality intermediates like Deferiprone. These companies often provide competitive pricing due to economies of scale and advanced manufacturing capabilities. When looking to purchase this compound, considering suppliers based in China can offer a cost-effective solution without compromising on quality, provided due diligence is performed.

In summary, Deferiprone (CAS 30652-11-0) is a cornerstone compound for research into iron metabolism and its associated diseases. By prioritizing purity and partnering with reliable manufacturers and suppliers, researchers and developers can access this critical chelator to advance their scientific endeavors.