Isonicotinic Acid: Synthesis Intermediate for Fexofenadine and Isoniazid Production
Isonicotinic acid, identified by its CAS number 55-22-1 and commonly known as 4-Pyridinecarboxylic acid, is a fundamental organic chemical that plays a crucial role as an intermediate in the synthesis of essential pharmaceuticals. Its molecular formula, C6H5NO2, and a molecular weight of 123.10900, describe a compound characterized by its crystalline powder form, appearing in white or light brown hues. The utility of this chemical is most prominently recognized in its application as a building block for medications that impact global health.
A primary area where isonicotinic acid demonstrates significant value is in the production of Fexofenadine. This active pharmaceutical ingredient (API) is a key component in many over-the-counter and prescription allergy medications. The synthesis pathway for Fexofenadine hydrochloride, a common derivative, critically relies on the availability of high-purity isonicotinic acid. Manufacturers aiming to produce Fexofenadine effectively must ensure their sourcing of isonicotinic acid meets strict quality parameters, often seeking suppliers from regions known for chemical manufacturing expertise, such as China.
Furthermore, isonicotinic acid is an indispensable intermediate for the synthesis of Isoniazid. This medication is a cornerstone in the treatment of tuberculosis, a persistent global health challenge. The consistent production of Isoniazid, a widely used first-line anti-tuberculosis drug, is directly dependent on a stable supply of high-quality isonicotinic acid. The ability to purchase this compound reliably is essential for pharmaceutical companies dedicated to combating infectious diseases.
The physical and chemical properties of isonicotinic acid, including its density (1.293g/cm³) and high melting point (≥300°C), underscore its chemical robustness. Its purity specification of ≥99% is a testament to its suitability for sensitive pharmaceutical synthesis processes. When considering where to buy this chemical, looking for suppliers that provide detailed technical data and adhere to stringent quality control is paramount. Manufacturers in China are often well-positioned to meet these demands.
In summary, isonicotinic acid is a vital link in the pharmaceutical supply chain, enabling the production of critical medications like Fexofenadine and Isoniazid. Its chemical profile and specific applications make it a sought-after intermediate for drug manufacturers worldwide. For those in the market to purchase this compound, focusing on purity and reliable sourcing from established manufacturers is key to ensuring the quality and availability of essential medicines.
A primary area where isonicotinic acid demonstrates significant value is in the production of Fexofenadine. This active pharmaceutical ingredient (API) is a key component in many over-the-counter and prescription allergy medications. The synthesis pathway for Fexofenadine hydrochloride, a common derivative, critically relies on the availability of high-purity isonicotinic acid. Manufacturers aiming to produce Fexofenadine effectively must ensure their sourcing of isonicotinic acid meets strict quality parameters, often seeking suppliers from regions known for chemical manufacturing expertise, such as China.
Furthermore, isonicotinic acid is an indispensable intermediate for the synthesis of Isoniazid. This medication is a cornerstone in the treatment of tuberculosis, a persistent global health challenge. The consistent production of Isoniazid, a widely used first-line anti-tuberculosis drug, is directly dependent on a stable supply of high-quality isonicotinic acid. The ability to purchase this compound reliably is essential for pharmaceutical companies dedicated to combating infectious diseases.
The physical and chemical properties of isonicotinic acid, including its density (1.293g/cm³) and high melting point (≥300°C), underscore its chemical robustness. Its purity specification of ≥99% is a testament to its suitability for sensitive pharmaceutical synthesis processes. When considering where to buy this chemical, looking for suppliers that provide detailed technical data and adhere to stringent quality control is paramount. Manufacturers in China are often well-positioned to meet these demands.
In summary, isonicotinic acid is a vital link in the pharmaceutical supply chain, enabling the production of critical medications like Fexofenadine and Isoniazid. Its chemical profile and specific applications make it a sought-after intermediate for drug manufacturers worldwide. For those in the market to purchase this compound, focusing on purity and reliable sourcing from established manufacturers is key to ensuring the quality and availability of essential medicines.
Perspectives & Insights
Data Seeker X
“In summary, isonicotinic acid is a vital link in the pharmaceutical supply chain, enabling the production of critical medications like Fexofenadine and Isoniazid.”
Chem Reader AI
“Its chemical profile and specific applications make it a sought-after intermediate for drug manufacturers worldwide.”
Agile Vision 2025
“For those in the market to purchase this compound, focusing on purity and reliable sourcing from established manufacturers is key to ensuring the quality and availability of essential medicines.”