Isopropyl 3-Aminocrotonate: A Deep Dive into its Chemical Properties and Synthesis Pathways
A thorough understanding of chemical intermediates is fundamental to advancements in chemistry and related industries. Isopropyl 3-aminocrotonate, known by its CAS number 14205-46-0, is a compound whose chemical properties and synthesis pathways are of significant interest. This molecule serves as a versatile organic synthesis building block and a crucial pharmaceutical intermediate. NINGBO INNO PHARMCHEM CO.,LTD. is a key supplier of this important chemical.
The chemical structure of Isopropyl 3-aminocrotonate, C7H13NO2, features an ester group and an amine group conjugated with a double bond. This arrangement imparts specific reactivity, making it valuable in numerous organic reactions. Typical synthesis methods involve reacting isopropyl acetoacetate with ammonium acetate under reflux conditions, followed by purification. High yields are often achievable, making it an efficient intermediate for large-scale pharmaceutical intermediates manufacturing. The purity of the final product is paramount, especially for pharmaceutical applications, and suppliers like NINGBO INNO PHARMCHEM CO.,LTD. ensure adherence to strict quality controls.
Key chemical properties include its appearance as a colorless to pale yellow liquid, a boiling point of approximately 80°C at 1 mmHg, and a melting point in the range of 19-23°C. These physical characteristics are important for its handling, storage, and processing in various applications. Its solubility in common organic solvents like chloroform, ethyl acetate, and methanol further enhances its utility in diverse synthesis processes. For those looking to buy isopropyl 3-aminocrotonate online, understanding these properties is essential for successful integration into their workflows.
The role of Isopropyl 3-aminocrotonate as an intermediate for drugs like nimodipine and irradipine highlights its importance in medicinal chemistry. However, its applications are not limited to pharmaceuticals; it also contributes to the synthesis of agrochemicals and other specialty chemicals. The continuous exploration of organic synthesis applications ensures that this compound remains relevant across multiple industries.
In summary, Isopropyl 3-aminocrotonate is a chemically rich molecule with well-defined properties and established synthesis routes. Its dual role as a pharmaceutical intermediate and a versatile organic synthesis building block makes it a valuable commodity for researchers and manufacturers alike.
Perspectives & Insights
Bio Analyst 88
“The continuous exploration of organic synthesis applications ensures that this compound remains relevant across multiple industries.”
Nano Seeker Pro
“In summary, Isopropyl 3-aminocrotonate is a chemically rich molecule with well-defined properties and established synthesis routes.”
Data Reader 7
“Its dual role as a pharmaceutical intermediate and a versatile organic synthesis building block makes it a valuable commodity for researchers and manufacturers alike.”