The field of medicinal chemistry continually explores novel molecular scaffolds to develop groundbreaking therapeutics. Among these, isoxazole derivatives have carved out a significant niche due to their versatile chemical properties and their presence in a wide array of biologically active compounds. One such compound, 4-[5-(4-(Pentyloxy)Phenyl)Isoxazol-3-yl]Benzoic Acid (CAS 179162-55-1), exemplifies the importance of these structures in pharmaceutical research and development, particularly as a critical intermediate for advanced drug synthesis.

The Chemical Versatility of Isoxazoles

Isoxazoles are five-membered heterocyclic aromatic rings containing one nitrogen and one oxygen atom adjacent to each other. This unique arrangement imparts specific electronic and steric properties that can be finely tuned through substitution. The compound 4-[5-(4-(Pentyloxy)Phenyl)Isoxazol-3-yl]Benzoic Acid incorporates this core structure, linking it to a benzoic acid moiety and a pentyloxy-substituted phenyl group. This structural complexity makes it an ideal intermediate for chemists aiming to build more elaborate molecules. Its utility is most notably recognized in the pharmaceutical sector, where it serves as a precursor in the synthesis of potent antifungal agents.

Application in Pharmaceutical Synthesis

The primary application of 4-[5-(4-(Pentyloxy)Phenyl)Isoxazol-3-yl]Benzoic Acid lies in its role as an intermediate for synthesizing Micafungin. This drug belongs to the echinocandin class, which targets the fungal cell wall synthesis pathway. The precise structure of this isoxazole derivative is critical for achieving the desired biological activity and pharmacological profile in the final API. For R&D scientists and procurement managers, sourcing this intermediate with guaranteed high purity (u226598.0%) and consistent quality is paramount. The availability of this compound from reliable manufacturers, often found in regions with strong chemical synthesis capabilities like China, supports the advancement of critical drug development projects.

Procurement and Supplier Considerations for R&D

When engaging in pharmaceutical R&D, accessing high-quality chemical building blocks is fundamental. For 4-[5-(4-(Pentyloxy)Phenyl)Isoxazol-3-yl]Benzoic Acid, researchers typically require it in quantities ranging from milligrams to kilograms, depending on the stage of development. It is crucial to buy from suppliers who can provide comprehensive technical data, including spectral information and purity analysis. Manufacturers offering GMP or ISO certifications often indicate a commitment to quality that is beneficial for R&D projects intended for eventual commercialization. Investigating suppliers based in China, for example, can lead to cost-effective solutions without compromising on quality, provided rigorous supplier vetting is performed.

The strategic use of isoxazole derivatives like 4-[5-(4-(Pentyloxy)Phenyl)Isoxazol-3-yl]Benzoic Acid highlights the ongoing innovation in medicinal chemistry. By understanding the properties and sourcing channels for these essential building blocks, pharmaceutical companies can accelerate their research and development efforts. For those in need of this specific intermediate, seeking out experienced manufacturers and suppliers who prioritize purity and reliability is the first step towards successful project outcomes.