For chemical buyers and pharmaceutical manufacturers, understanding the precise specifications and sourcing strategies for key intermediates like Ketotifen Fumarate (CAS 34580-14-8) is critical. This compound is a vital building block in the pharmaceutical industry, primarily utilized for its potent anti-allergic properties.

Ketotifen Fumarate is characterized chemically by its structure as a thiatricyclo[8.4.0.03,7]tetradeca-1(14),3(7),4,10,12-pentaen-8-one derivative, with a molecular formula of C23H23NO5S and a molecular weight of 425.5 g/mol. Typically, it appears as a white or off-white crystalline powder, and its purity is usually specified as ≥98%. This high level of purity is essential for its use in pharmaceutical applications, especially in the formulation of ophthalmic solutions aimed at treating allergic conjunctivitis. When seeking to buy Ketotifen Fumarate, these physical and chemical attributes are primary considerations for quality assurance.

The therapeutic value of Ketotifen Fumarate lies in its dual action: it acts as a histamine H1-receptor antagonist and a mast cell stabilizer. This makes it highly effective in managing allergic reactions by blocking the effects of histamine and preventing the release of inflammatory mediators. Its role in developing eye drops for itchy eyes due to allergies is well-established, making it a sought-after ingredient for pharmaceutical companies. For researchers, it's also valuable for investigating new allergy treatment modalities.

When sourcing this intermediate, chemical buyers often look for competitive pricing and reliable supply chains. Searching for 'Ketotifen Fumarate supplier China' is a common strategy, given China's substantial chemical manufacturing infrastructure. Prospective buyers should carefully vet potential manufacturers, considering factors such as their experience in API production, adherence to quality standards, and the availability of comprehensive technical documentation. A supplier’s ability to consistently provide material that meets specifications is paramount.

In conclusion, Ketotifen Fumarate is a significant pharmaceutical intermediate, crucial for the development of effective allergy treatments. For chemical buyers and pharmaceutical manufacturers looking to purchase this vital API, focusing on purity, supplier reliability, and competitive pricing is essential. Engaging with reputable manufacturers and suppliers, particularly those based in China, can ensure a steady supply of high-quality Ketotifen Fumarate, thereby supporting the development of advanced therapeutic solutions.