Boc-(R)-3-Amino-4-(2,4-dichlorophenyl)butyric acid (CAS: 269396-53-4) is a highly valuable chemical intermediate that plays a significant role in various scientific disciplines, particularly in pharmaceutical research and advanced organic synthesis. Its unique structural features, including the Boc-protected amine and the chiral center, make it an indispensable tool for chemists aiming to construct complex molecules with precision.

Pharmaceutical Development: A Cornerstone Building Block

One of the most prominent applications for Boc-(R)-3-Amino-4-(2,4-dichlorophenyl)butyric acid is in the synthesis of Active Pharmaceutical Ingredients (APIs). Pharmaceutical companies actively seek high-purity chiral intermediates like this one to build drug candidates. The presence of the dichloro-substituted phenyl ring offers opportunities for further functionalization or influences the molecule's pharmacokinetic properties. Researchers looking to buy this compound for drug discovery often find it crucial for developing novel therapeutics, especially in areas where specific stereochemistry is critical for biological activity.

Advancing Organic Synthesis

Beyond pharmaceuticals, this compound serves as a versatile building block in general organic synthesis. Chemists utilize it to introduce specific structural motifs into larger molecules. The Boc protecting group is readily removed under acidic conditions, revealing the free amine for subsequent coupling or modification reactions. Its utility extends to the synthesis of complex natural products or specialized organic materials where a chiral center with a bulky, functionalized side chain is required. Any scientist needing to purchase these specialized reagents can find reliable manufacturers and suppliers globally.

The Importance of Chiral Purity

The 'R' designation in Boc-(R)-3-Amino-4-(2,4-dichlorophenyl)butyric acid signifies its specific stereochemical configuration. In pharmaceutical applications and chiral synthesis, enantiomeric purity is often critical, as different enantiomers can exhibit vastly different biological activities or chemical properties. Therefore, sourcing this compound from a reputable manufacturer that guarantees high enantiomeric excess (ee) is paramount. Procurement managers should always request certificates of analysis to confirm the chiral purity of the material.

Where to Buy and Price Considerations

When considering where to buy Boc-(R)-3-Amino-4-(2,4-dichlorophenyl)butyric acid, it's beneficial to look for manufacturers and suppliers who specialize in fine chemicals and pharmaceutical intermediates. Countries like China are significant hubs for chemical manufacturing, offering competitive pricing and a wide range of products. For accurate pricing, it is advisable to request a formal quote directly from the supplier, specifying the quantity and purity requirements.

In conclusion, Boc-(R)-3-Amino-4-(2,4-dichlorophenyl)butyric acid is a highly sought-after intermediate due to its structural features and versatility. Its application in pharmaceutical development and organic synthesis underscores its importance in modern chemical research.