In the intricate world of chemical manufacturing, certain compounds stand out for their versatility and essential role in producing higher-value products. Levamisole Hydrochloride, identified by its CAS number 16595-80-5, is one such critical intermediate. Its physical form as a white to almost white crystalline powder, coupled with its solubility characteristics, makes it a prime candidate for various synthetic pathways, particularly within the pharmaceutical and veterinary industries.

Chemical Profile and Properties

Levamisole Hydrochloride, with the chemical formula C11H12N2S.HCl and a molecular weight of 240.77, is a derivative of imidazo[2,1-b]thiazole. Its notable solubility in water (210 g/L at 20 ºC) is a significant advantage in chemical processing. This property allows for its convenient use in aqueous reaction media, which are often preferred for safety and environmental reasons. Understanding these properties is key for R&D scientists and formulators when planning their synthesis routes.

Primary Applications and Importance

The primary value of Levamisole Hydrochloride lies in its role as a pharmaceutical intermediate. It serves as a fundamental building block for the synthesis of various Active Pharmaceutical Ingredients (APIs). Its immunomodulatory and anthelmintic properties, though sometimes utilized directly, are more commonly leveraged through its transformation into more complex therapeutic agents. For manufacturers of generic drugs and novel pharmaceuticals, securing a reliable source of this intermediate is crucial for maintaining production continuity.

Why Manufacturers Rely on Levamisole Hydrochloride

  • Synthetic Versatility: The reactive sites within the molecule allow for a wide range of chemical modifications.
  • Established Supply Chains: As a well-known intermediate, there are established manufacturing bases, particularly in China, offering good supply chain reliability.
  • Cost-Effectiveness: Compared to highly specialized or novel intermediates, Levamisole Hydrochloride is often more cost-effective, especially when purchased in bulk from dedicated manufacturers.

Sourcing Levamisole Hydrochloride

For businesses looking to buy Levamisole Hydrochloride (CAS 16595-80-5), partnering with a reputable manufacturer is paramount. Key factors to consider include production capacity, quality control (purity levels, COAs), and export experience. Companies seeking to purchase this chemical should inquire about minimum order quantities, pricing structures for bulk orders, and shipping arrangements. Engaging with a supplier in China, a major global producer, can often provide access to competitive pricing and a stable supply of this important intermediate.

In conclusion, Levamisole Hydrochloride is more than just a chemical; it's a cornerstone intermediate that empowers the pharmaceutical industry to develop and produce essential medicines. Its consistent availability and predictable properties make it a vital component for manufacturers worldwide.