For chemists and engineers engaged in advanced synthesis, a thorough understanding of a chemical intermediate's properties and accessible synthesis routes is paramount. 3,5-Difluorobenzonitrile, identified by CAS number 64248-63-1, is a fluorinated aromatic nitrile that offers a compelling combination of chemical reactivity and structural utility. If your organization is considering its use or looking to buy this compound, appreciating its key characteristics and how it's produced is essential. As a dedicated manufacturer, we offer insights into this valuable intermediate.

The physical and chemical properties of 3,5-difluorobenzonitrile make it highly desirable for various applications. It typically appears as a white to off-white crystalline solid, with a melting point in the range of 84-86°C. Its molecular formula is C7H3F2N, and its molecular weight is approximately 139.10 g/mol. The presence of two fluorine atoms in the meta positions significantly influences the electron density distribution within the molecule, enhancing its electron-withdrawing nature. This makes it an excellent candidate for nucleophilic aromatic substitution reactions and a valuable component in materials science where precise electronic properties are required.

Regarding its synthesis, 3,5-difluorobenzonitrile can be effectively prepared through established organic synthesis methodologies. One common route involves the conversion of a precursor like 3,5-difluorobromobenzene. The process often includes reactions like Grignard formation followed by reaction with dimethylformamide (DMF) and subsequent functionalization. Manufacturers like ourselves employ optimized synthesis protocols to ensure high yields and purity, typically exceeding 99%. This rigorous approach is critical for meeting the demands of industries like pharmaceuticals and advanced materials.

The utility of 3,5-difluorobenzonitrile extends to its role as a critical building block in creating complex molecules. In medicinal chemistry, it is used to synthesize drug candidates that benefit from the metabolic stability and altered binding affinities conferred by fluorine atoms. In electronic materials, it is incorporated into structures for OLEDs and liquid crystals, influencing charge transport and luminescent properties. For those looking to buy this intermediate, understanding these synthesis-dependent properties can guide its selection for specific project needs.

As a global supplier, we ensure that our production processes are efficient and environmentally conscious, aiming to provide a reliable and cost-effective supply of 3,5-difluorobenzonitrile. Procurement teams and R&D chemists seeking to leverage the unique properties of this compound should consider partnering with manufacturers who prioritize quality and offer consistent product availability. We are committed to supporting your research and development endeavors with our expertise and high-quality chemical intermediates. Feel free to contact us to learn more about the chemical properties and purchase options for 3,5-difluorobenzonitrile.