In the intricate world of organic chemistry and pharmaceutical development, the availability of high-quality building blocks is paramount. Among these crucial compounds, fluorinated intermediates play a significant role due to the unique properties fluorine imparts to molecules, such as increased metabolic stability and lipophilicity. One such vital intermediate is 1-(2-Bromoethyl)-4-fluorobenzene, identified by its CAS number 332-42-3.

This article delves into the significance of 1-(2-Bromoethyl)-4-fluorobenzene, its applications, and the strategic advantage of sourcing it from reputable manufacturers and suppliers, particularly those based in China. For R&D scientists and procurement managers, understanding where to buy these essential chemicals can significantly impact project timelines and success rates. We aim to provide insight into why a robust supply chain for compounds like CAS 332-42-3 is critical.

Understanding 1-(2-Bromoethyl)-4-fluorobenzene (CAS 332-42-3)

1-(2-Bromoethyl)-4-fluorobenzene, also known by synonyms such as 4-Fluorophenethyl bromide, is a halogenated aromatic compound. Its molecular structure, C8H8BrF, and molecular weight of approximately 203.05 g/mol, make it a versatile tool in synthetic chemistry. Its physical properties, often described as a clear to slightly yellow liquid with a boiling point around 100-104°C at 15 mmHg, are important for handling and reaction optimization. The presence of both a bromine atom and a fluorine atom on the phenyl ring provides distinct reactivity points, making it invaluable for a range of chemical transformations.

The utility of this compound spans several critical areas:

  • Pharmaceutical Intermediates: It serves as a key intermediate in the synthesis of various pharmaceutical agents. For example, it has been used in the development of protein A mimetics and serotonin antagonists, which are important for treating neurological and other medical conditions. The demand for high-purity intermediates like 332-42-3 is constant in the pharmaceutical sector.
  • Organic Synthesis: Beyond pharmaceuticals, it acts as a valuable building block in broader organic synthesis, enabling the construction of complex molecules for materials science, agrochemicals, and specialty chemicals.
  • Research and Development: Academic institutions and industrial R&D departments rely on consistent access to such compounds for exploring new chemical entities and synthetic methodologies.

The Strategic Advantage of Sourcing from China

For many businesses globally, China has emerged as a premier source for chemical manufacturing and supply. The country boasts a vast and sophisticated chemical industry, offering a wide array of intermediates at competitive prices. When looking to buy 1-(2-Bromoethyl)-4-fluorobenzene, sourcing from a reputable Chinese manufacturer or supplier provides several benefits:

  • Cost-Effectiveness: Chinese manufacturers often offer lower production costs, translating to more affordable prices for bulk purchases of intermediates like CAS 332-42-3. This allows research institutions and companies to stretch their budgets further or acquire larger quantities for their projects.
  • Scalability and Availability: The sheer scale of chemical production in China means that even significant quantities of intermediates can be manufactured and supplied reliably. This is crucial for companies scaling up production or requiring consistent supply for ongoing research.
  • Quality Assurance: While cost is a factor, quality cannot be compromised. Leading Chinese chemical suppliers adhere to international quality standards, providing products with guaranteed purity (often 95%min or higher, as confirmed by GC analysis). Certificates of Analysis (CoA) are typically provided, assuring the quality of the product.
  • Established Supply Chains: Many Chinese chemical companies have well-developed export logistics, ensuring timely delivery to international destinations. This reduces lead times and improves the efficiency of your procurement process.

When evaluating suppliers for 1-(2-Bromoethyl)-4-fluorobenzene, it is essential to look for manufacturers that emphasize product purity, consistent quality, and responsive customer service. For instance, companies offering free samples can allow R&D teams to verify the product's suitability before committing to larger orders.

Choosing the Right Supplier for Your Needs

For procurement managers and research scientists seeking to purchase 1-(2-Bromoethyl)-4-fluorobenzene (CAS 332-42-3), partnering with an experienced manufacturer in China can be a strategic move. These suppliers often have extensive experience in custom synthesis and can cater to specific purity requirements or packaging needs. They understand the critical nature of these materials in the R&D pipeline and strive to provide not just a product, but a reliable solution.

When you inquire about the price or availability of this essential organic building block, remember to specify your required quantity and purity. A good supplier will promptly provide a quotation, along with details on lead times and shipping. Their commitment should extend to offering technical support and ensuring compliance with regulatory requirements.

In conclusion, 1-(2-Bromoethyl)-4-fluorobenzene (CAS 332-42-3) is a highly sought-after intermediate in the chemical industry, particularly for pharmaceutical synthesis. By strategically sourcing this compound from reputable Chinese manufacturers and suppliers, businesses can secure high-purity materials at competitive prices, ensuring the smooth progression of their research and development projects.