Key Intermediate: N-tert-butoxycarbonyl-L-lysine Methyl Ester HCl
In the vast landscape of organic chemistry and pharmaceutical development, specific intermediates play pivotal roles in enabling the creation of complex molecules. N-tert-butoxycarbonyl-L-lysine methyl ester hydrochloride, commonly known by its CAS number 55757-60-3, is one such critical compound. This protected amino acid derivative is indispensable in the field of peptide synthesis, serving as a fundamental building block for a wide array of applications in drug discovery, biotechnology, and advanced materials research. Understanding its properties and sourcing channels is crucial for researchers and procurement specialists.
The primary utility of N-tert-butoxycarbonyl-L-lysine methyl ester hydrochloride lies in its role as a protected form of the amino acid lysine. Lysine is a naturally occurring amino acid with a reactive side-chain amino group, in addition to its alpha-amino and alpha-carboxyl groups. During the process of peptide synthesis, where amino acids are linked together in a specific sequence, it is essential to prevent unwanted reactions at these multiple functional sites. The 'Boc' (tert-butoxycarbonyl) protecting group is strategically attached to the alpha-amino group, and the methyl ester is used to protect the carboxyl group. This dual protection ensures that lysine can be selectively incorporated into a growing peptide chain without interference, allowing chemists to build peptides with high fidelity and yield. When you seek to purchase N-tert-butoxycarbonyl-L-lysine methyl ester hydrochloride, specifying the CAS number 55757-60-3 is key to obtaining the correct, high-quality material.
The hydrochloride salt form of this compound often enhances its solubility and handling characteristics in common organic solvents used in synthesis. This makes it a practical reagent for both laboratory-scale research and larger-scale manufacturing processes. The ability to buy this intermediate from reliable manufacturers, especially those with expertise in producing pharmaceutical intermediates, is critical. A consistent supply of pure N-tert-butoxycarbonyl-L-lysine methyl ester hydrochloride from a reputable manufacturer ensures that your drug development projects maintain momentum and product quality.
Beyond its direct use in peptide synthesis, this compound can also serve as a precursor for synthesizing various lysine-containing biomolecules, peptide mimetics, and conjugates used in targeted drug delivery systems or diagnostics. Its versatility makes it a sought-after reagent for a wide spectrum of chemical and biological research endeavors.
For those looking to procure N-tert-butoxycarbonyl-L-lysine methyl ester hydrochloride, understanding the market and identifying trusted suppliers is paramount. Factors such as purity (often stated as >98% or >99% TLC), packaging, and lead times are important considerations. Exploring options for bulk quotations from leading chemical suppliers in regions like China can offer significant cost advantages without compromising on quality. Engaging with manufacturers who provide detailed technical data and certificates of analysis ensures that you are acquiring a product that meets rigorous industry standards, thereby supporting the successful execution of your research and development objectives.
Perspectives & Insights
Agile Reader One
“Factors such as purity (often stated as >98% or >99% TLC), packaging, and lead times are important considerations.”
Logic Vision Labs
“Exploring options for bulk quotations from leading chemical suppliers in regions like China can offer significant cost advantages without compromising on quality.”
Molecule Origin 88
“Engaging with manufacturers who provide detailed technical data and certificates of analysis ensures that you are acquiring a product that meets rigorous industry standards, thereby supporting the successful execution of your research and development objectives.”