In the intricate world of chemical synthesis, identifying and securing reliable sources for key intermediates is fundamental to innovation and production. (5-Formylfuran-2-yl)boronic acid, identified by its CAS number 27329-70-0, stands out as a valuable and versatile compound, particularly for those in the pharmaceutical and fine chemical industries. Understanding its characteristics and applications is crucial for procurement managers and R&D scientists aiming to optimize their supply chains.

Chemical Profile and Properties

(5-Formylfuran-2-yl)boronic acid possesses a molecular formula of C5H5BO4 and a molecular weight of approximately 139.90. Its physical appearance is typically described as an off-white to pale yellow to pink crystalline powder, indicating its solid state at room temperature. This form is advantageous for handling, storage, and precise weighing in laboratory and industrial settings. The product's key chemical features include a furan ring, an aldehyde group (-CHO), and a boronic acid group (-B(OH)2). This trifecta of functionalities makes it a reactive and adaptable molecule for a wide range of organic transformations. Its melting point is reported around 136°C, and a flash point of 183.2°C signifies moderate flammability characteristics.

Applications in Synthesis: A Versatile Intermediate

The primary utility of (5-formylfuran-2-yl)boronic acid lies in its role as a sophisticated building block for more complex molecules. Its most prominent application is as a crucial intermediate in the synthesis of Lapatinib, a targeted therapy drug used to treat certain types of cancer. In this context, the precise structure and reactivity of the boronic acid derivative are vital for achieving the desired API. Furthermore, the boronic acid moiety is a cornerstone of Suzuki-Miyaura cross-coupling reactions, a powerful tool for forming carbon-carbon bonds. This capability allows chemists to attach the formyl-substituted furan unit to various organic scaffolds, making it valuable for drug discovery, agrochemical development, and material science research. When you need to buy such a functionalized furan derivative, ensuring its availability and quality from a reliable supplier is paramount.

Procurement Considerations: Quality and Supply

For businesses seeking to buy (5-formylfuran-2-yl)boronic acid, understanding the market and supplier landscape is essential. The typical purity required is ≥98.0%, ensuring that the material is suitable for demanding synthetic pathways. Manufacturers often offer this intermediate in standard packaging like 25 kg drums, with options for custom packaging to meet specific customer needs. As a manufacturer and supplier, our focus is on providing consistent quality and reliable availability. We understand that for R&D scientists and procurement managers, a dependable supply chain for key intermediates like (5-formylfuran-2-yl)boronic acid is critical for continuous operations and successful project timelines. Engaging with experienced manufacturers allows for competitive pricing and dedicated support.

(5-Formylfuran-2-yl)boronic acid is a testament to the ingenuity of organic chemistry, offering a unique combination of reactivity and structural features that make it indispensable in modern synthesis. We are committed to supplying this vital intermediate to support your chemical and pharmaceutical endeavors.