The pharmaceutical industry constantly seeks innovative compounds and efficient synthesis routes to develop life-saving medications. At the heart of many groundbreaking drug discoveries lies a range of specialized chemical intermediates. Among these, 4-Amino-2-Fluorobenzotrifluoride (CAS: 69411-68-3) stands out for its significant contribution to modern medicinal chemistry. This article aims to provide researchers and procurement specialists with a comprehensive understanding of this vital compound, its properties, applications, and the importance of sourcing it from trusted manufacturers.

What is 4-Amino-2-Fluorobenzotrifluoride?

Also known as 3-fluoro-4-(trifluoromethyl)aniline, this chemical compound is a key building block primarily used as a pharmaceutical intermediate. Its molecular formula, C7H5F4N, and molecular weight of 179.11500 highlight a structure designed for specific reactivity in complex organic syntheses. The presence of fluorine atoms and a trifluoromethyl group on the benzene ring imparts unique chemical characteristics, including enhanced lipophilicity and metabolic stability. These features are highly advantageous in drug design, as they can improve a drug candidate's pharmacokinetic profile, leading to better bioavailability and therapeutic efficacy.

Chemical and Physical Profile for Practical Use

Understanding the physical attributes of 4-Amino-2-Fluorobenzotrifluoride is crucial for handling and application. It is typically supplied as a white powder, with a purity level of at least 98.0%. Key properties include a melting point of 55°C, a boiling point of 203.8°C at 760 mmHg, and a density of 1.383 g/cm³. These parameters ensure its stability under standard laboratory and industrial conditions. For optimal preservation of its quality, it is recommended to store the compound in a tightly closed container in a cool, dry environment.

Applications in Pharmaceutical Synthesis

The primary application of 4-Amino-2-Fluorobenzotrifluoride is its role as a precursor in the synthesis of various Active Pharmaceutical Ingredients (APIs). Medicinal chemists leverage its unique structure to incorporate fluorinated moieties into drug molecules, a strategy proven to enhance potency, selectivity, and metabolic resistance. If you are looking to buy pharmaceutical intermediates, this compound is a prime candidate for your research and development pipeline. Its versatility makes it valuable for creating APIs targeting a wide range of therapeutic areas.

Sourcing and Reliability: The Manufacturer's Role

For businesses requiring this intermediate, identifying a reliable manufacturer of 4-Amino-2-Fluorobenzotrifluoride is paramount. A reputable supplier will guarantee high purity, consistent quality, and efficient delivery. As a leading API intermediate supplier, we pride ourselves on our commitment to quality control and our ability to provide large quantities of this essential chemical. We understand that the price of 4-Amino-2-Fluorobenzotrifluoride can be a significant factor, and we strive to offer competitive pricing without compromising on quality.

When you are ready to purchase 3-fluoro-4-(trifluoromethyl)aniline, engaging directly with manufacturers in China can provide significant advantages. These include access to advanced production facilities, experienced R&D teams, and competitive market pricing. We are a trusted partner for many global pharmaceutical and biotech companies, offering not just products but also expertise.

In summary, 4-Amino-2-Fluorobenzotrifluoride is an indispensable compound in modern pharmaceutical chemistry. By understanding its properties and applications, and by partnering with dependable suppliers, R&D professionals can ensure the seamless progression of their drug development projects. We invite you to explore our offerings and discover how we can support your chemical sourcing needs.