In the intricate world of pharmaceutical manufacturing, the quality and availability of chemical intermediates are paramount. Among these crucial compounds, 4,6-Dichloro-2-methylpyrimidine (CAS 1780-26-3) stands out as a versatile and indispensable building block. For R&D scientists, product formulators, and procurement managers, understanding its properties and sourcing strategies is key to successful drug development.

This pyrimidine derivative, with its distinct chemical structure, plays a vital role in the synthesis of several significant Active Pharmaceutical Ingredients (APIs). Notably, it is a key intermediate in the production of Dasatinib, a life-saving tyrosine kinase inhibitor used in the treatment of certain leukemias. The demand for high-purity 4,6-Dichloro-2-methylpyrimidine in this application underscores the need for reliable suppliers who can guarantee consistent quality and specifications.

Beyond oncology, this compound is also a cornerstone in the synthesis of Moxonidine, a widely used anti-hypertensive medication. The efficacy and safety of Moxonidine are directly linked to the quality of its precursors, making the choice of manufacturer for 4,6-Dichloro-2-methylpyrimidine a critical decision. Procurement managers often seek out manufacturers in China due to competitive pricing and robust manufacturing capabilities.

When looking to buy 4,6-Dichloro-2-methylpyrimidine, professionals focus on several key attributes: purity (typically ≥99%), consistent assay values, and minimal impurities. Factors such as physical appearance (often an off-white crystalline powder) and proper storage conditions are also important considerations. Understanding the CAS number, 1780-26-3, is essential for accurate identification and sourcing.

For those seeking to secure a stable supply of this critical intermediate, partnering with experienced manufacturers is highly recommended. The ability to obtain a quote and understand the price per unit or per kilogram is crucial for budgeting and project planning. Furthermore, a reliable supplier ensures timely delivery, mitigating potential delays in research timelines or production schedules. Whether for research quantities or bulk purchase, the focus remains on quality assurance and supply chain reliability. By prioritizing these aspects, pharmaceutical companies can ensure the smooth progression of their drug development pipelines.