In the intricate landscape of pharmaceutical development and manufacturing, the quality and availability of key intermediates are paramount. These chemical compounds serve as the essential building blocks for Active Pharmaceutical Ingredients (APIs), and their reliable supply is critical for bringing effective medicines to market. Ethyl 2-aminothiazole-5-carboxylate (CAS: 32955-21-8) is a significant pharmaceutical intermediate, widely recognized for its utility in synthesizing important therapeutic agents.

This compound, a derivative of thiazole, is characterized by its molecular formula C6H8N2O2S and a molecular weight of 172.20 g/mol. It typically presents as a light yellow to yellow powder, with a confirmed purity assay of ≥98.0%. These specifications are crucial for its application in demanding pharmaceutical synthesis processes, where precise molecular structures and minimal impurities are essential for the quality of the final drug product.

The primary and most notable application of Ethyl 2-aminothiazole-5-carboxylate is its indispensable role in the synthesis of Dasatinib. Dasatinib is a targeted therapy drug that has proven effective in treating certain forms of leukemia, specifically chronic myeloid leukemia (CML) and Philadelphia chromosome-positive acute lymphoblastic leukemia (Ph+ ALL). The efficient and high-yield synthesis of Dasatinib directly depends on the quality and availability of this specific intermediate. Therefore, pharmaceutical companies and contract manufacturing organizations (CMOs) often seek robust supply chains for this compound.

For businesses looking to purchase Ethyl 2-aminothiazole-5-carboxylate, several factors are critical when selecting a supplier. These include:

  • Purity and Quality Assurance: Ensuring the intermediate meets the required assay and impurity profile is non-negotiable for pharmaceutical use.
  • Supply Reliability: A consistent and dependable supply chain is vital for uninterrupted production schedules.
  • Competitive Pricing: Sourcing from manufacturers, especially those in established chemical production hubs like China, can offer significant cost advantages.
  • Technical Support and Documentation: Access to Certificates of Analysis (CoA) and responsive customer service enhances the purchasing experience and ensures regulatory compliance.

As a specialized manufacturer and supplier of pharmaceutical intermediates, we are committed to providing high-quality Ethyl 2-aminothiazole-5-carboxylate. Our focus on stringent quality control, coupled with competitive pricing and reliable supply capabilities, makes us an ideal partner for companies involved in pharmaceutical synthesis. We understand the critical nature of this intermediate for drugs like Dasatinib and are dedicated to supporting your manufacturing needs.

If your research or production requires high-purity Ethyl 2-aminothiazole-5-carboxylate, we encourage you to reach out to us to discuss your specific requirements and explore partnership opportunities. Securing a reliable source for this key intermediate is a strategic step towards successful pharmaceutical development.