The procurement of pharmaceutical intermediates is a critical function for any drug development and manufacturing company. Among these vital compounds is 4-Methoxyphenylacetic Acid (CAS: 104-01-8), a chemical that plays a significant role in synthesizing important APIs. This article aims to equip procurement managers with the essential information needed to source this compound effectively, focusing on quality, suppliers, and pricing, especially from manufacturers in China.

Understanding the Value of 4-Methoxyphenylacetic Acid

4-Methoxyphenylacetic Acid, also recognized as Homoanisic Acid, is primarily valued for its role as a precursor in the synthesis of Dextromethorphan, a widely recognized antitussive agent. The compound's chemical specifications, including its form as a white to off-white crystalline powder and an assay of ≥98.0%, are crucial indicators of its suitability for pharmaceutical applications. A high assay ensures that the subsequent synthesis steps are clean and efficient, minimizing impurities in the final API. The melting point of 84-86°C further solidifies its identity and purity.

The Procurement Process: What to Expect

When you decide to buy 4-Methoxyphenylacetic Acid, the procurement process involves several key steps. Firstly, identify reputable manufacturers who specialize in pharmaceutical intermediates. Many leading suppliers are based in China, offering competitive pricing and large-scale production capabilities. Secondly, rigorously evaluate potential suppliers. Request detailed product specifications, Certificates of Analysis (CoA), and inquire about their quality management systems. Understanding the product's physical and chemical properties is essential for ensuring it meets your specific needs.

Factors Influencing Price and Supply

The price of 4-Methoxyphenylacetic Acid is influenced by several market dynamics, including global demand for Dextromethorphan, raw material costs, and the supplier's production capacity. Procurement managers seeking to purchase this intermediate should actively compare quotes from multiple sources. Leveraging relationships with established suppliers in China can often yield the best value, providing both quality and cost efficiency. It’s also important to discuss packaging options (e.g., 25 kg drums) and delivery timelines to ensure a seamless integration into your supply chain.

For companies in the pharmaceutical sector, securing a reliable and high-quality supply of 4-Methoxyphenylacetic Acid is a strategic imperative. By focusing on robust supplier evaluation and understanding market pricing, procurement teams can ensure their manufacturing processes are supported by the best available chemical intermediates.