Key Pharmaceutical Intermediates: Sourcing (S)-4-Chloro-3-hydroxybutyronitrile
The pharmaceutical industry's success hinges on the precise and consistent production of life-saving medications. At the heart of this complex process lies the critical role of pharmaceutical intermediates – the chemical building blocks that are synthesized and refined before being incorporated into the final active pharmaceutical ingredient (API). Among these essential components, chiral intermediates like (S)-4-Chloro-3-hydroxybutyronitrile (CAS 127913-44-4) hold particular significance.
(S)-4-Chloro-3-hydroxybutyronitrile is a valuable chemical reagent, recognized for its utility in various organic synthesis pathways, especially within the pharmaceutical sector. Its molecular structure, C4H6ClNO, with a molecular weight of 119.55, features both a hydroxyl group and a nitrile group, alongside a chiral center. This specific structural arrangement makes it an ideal starting material for constructing more complex chiral molecules required for targeted drug therapies.
One of the primary applications of this compound is as a precursor in the synthesis of atorvastatin, a blockbuster drug used to manage high cholesterol. The correct stereochemistry, provided by the (S) enantiomer of 4-Chloro-3-hydroxybutyronitrile, is essential for the drug's pharmacological activity. Similarly, it has been noted as an impurity in the synthesis of Rosuvastatin, another important cholesterol-lowering medication, highlighting its relevance in the production processes of major cardiovascular drugs.
For pharmaceutical companies, securing a reliable supply of high-purity (S)-4-Chloro-3-hydroxybutyronitrile is not just a logistical necessity but a quality imperative. Issues with purity or stereochemical integrity can lead to costly batch failures, regulatory hurdles, and delays in bringing vital medications to patients. Therefore, partnering with reputable manufacturers and suppliers in China, known for their expertise in fine chemical production, is a strategic advantage.
NINGBO INNO PHARMCHEM CO.,LTD. understands the demanding standards of the pharmaceutical industry. We are dedicated to providing high-quality (S)-4-Chloro-3-hydroxybutyronitrile, ensuring that our clients receive materials that meet their exact specifications. Whether you need to buy (S)-4-Chloro-3-hydroxybutyronitrile for research or large-scale manufacturing, our commitment to excellence guarantees a dependable supply of this crucial pharmaceutical intermediate.
(S)-4-Chloro-3-hydroxybutyronitrile is a valuable chemical reagent, recognized for its utility in various organic synthesis pathways, especially within the pharmaceutical sector. Its molecular structure, C4H6ClNO, with a molecular weight of 119.55, features both a hydroxyl group and a nitrile group, alongside a chiral center. This specific structural arrangement makes it an ideal starting material for constructing more complex chiral molecules required for targeted drug therapies.
One of the primary applications of this compound is as a precursor in the synthesis of atorvastatin, a blockbuster drug used to manage high cholesterol. The correct stereochemistry, provided by the (S) enantiomer of 4-Chloro-3-hydroxybutyronitrile, is essential for the drug's pharmacological activity. Similarly, it has been noted as an impurity in the synthesis of Rosuvastatin, another important cholesterol-lowering medication, highlighting its relevance in the production processes of major cardiovascular drugs.
For pharmaceutical companies, securing a reliable supply of high-purity (S)-4-Chloro-3-hydroxybutyronitrile is not just a logistical necessity but a quality imperative. Issues with purity or stereochemical integrity can lead to costly batch failures, regulatory hurdles, and delays in bringing vital medications to patients. Therefore, partnering with reputable manufacturers and suppliers in China, known for their expertise in fine chemical production, is a strategic advantage.
NINGBO INNO PHARMCHEM CO.,LTD. understands the demanding standards of the pharmaceutical industry. We are dedicated to providing high-quality (S)-4-Chloro-3-hydroxybutyronitrile, ensuring that our clients receive materials that meet their exact specifications. Whether you need to buy (S)-4-Chloro-3-hydroxybutyronitrile for research or large-scale manufacturing, our commitment to excellence guarantees a dependable supply of this crucial pharmaceutical intermediate.
Perspectives & Insights
Silicon Analyst 88
“This specific structural arrangement makes it an ideal starting material for constructing more complex chiral molecules required for targeted drug therapies.”
Quantum Seeker Pro
“One of the primary applications of this compound is as a precursor in the synthesis of atorvastatin, a blockbuster drug used to manage high cholesterol.”
Bio Reader 7
“The correct stereochemistry, provided by the (S) enantiomer of 4-Chloro-3-hydroxybutyronitrile, is essential for the drug's pharmacological activity.”