Methyl 3-amino-4-methylthiophene-2-carboxylate (CAS: 85006-31-1) is a fine chemical with significant utility in organic synthesis and the pharmaceutical industry. As a key intermediate, its precise characterization and availability are crucial for researchers and manufacturers alike. This article outlines its essential properties and primary applications, guiding potential buyers on sourcing this vital compound. When seeking to purchase this chemical, understanding its specifications ensures that your procurement aligns with your project requirements.

The physical appearance of Methyl 3-amino-4-methylthiophene-2-carboxylate is typically described as a white to light yellow crystal powder. Its molecular formula is C7H9NO2S, with a molecular weight of 171.22. Key physical properties include a melting point range of 85-88°C, indicating it is a solid at standard room temperature. Solubility data suggests it is slightly soluble in chloroform and methanol, which is important information for chemists designing reaction or purification protocols. The compound's EINECS number is 285-060-8, further aiding in identification.

The principal application of this thiophene derivative lies in its role as a starting material for the synthesis of articaine, a local anesthetic. This connection makes it a high-demand pharmaceutical intermediate. Beyond this, it serves as a versatile building block in various organic synthesis pathways, facilitating the creation of complex heterocyclic structures. For instance, it has been used to prepare certain thieno[3,2-d]pyrimidin-4(3H)-one derivatives, showcasing its broad applicability in medicinal chemistry research.

When sourcing this chemical, buyers often look for reliable suppliers, especially those who can provide consistent quality and competitive pricing. Many chemical manufacturers, particularly in regions like China, specialize in producing such intermediates. Thoroughly reviewing supplier credentials, checking purity specifications, and requesting quotes are essential steps before making a purchase. Whether for laboratory research or larger-scale production, securing a dependable source for Methyl 3-amino-4-methylthiophene-2-carboxylate ensures the efficiency and success of your synthetic endeavors.