Key Specifications for Sourcing Methyl N-[(2'-cyano-4-biphenylyl)methyl]-L-valinate
The precise quality of pharmaceutical intermediates directly dictates the success and safety of the final drug product. For N-[(2'-Cyano[1,1'-biphenyl]-4-yl)methyl]-L-valine methyl ester (CAS 137863-89-9), often referred to as Methyl N-[(2'-cyano-4-biphenylyl)methyl]-L-valinate, understanding key specifications is vital for procurement managers and R&D scientists. This intermediate is a cornerstone in the synthesis of Valsartan, a critical cardiovascular medication, making its quality paramount.
When evaluating suppliers, particularly manufacturers in China, several specifications for N-[(2'-Cyano[1,1'-biphenyl]-4-yl)methyl]-L-valine methyl ester should be a primary focus. Purity is, arguably, the most critical parameter. Typically, pharmaceutical-grade intermediates require a purity level of 99% or higher, often confirmed by analytical techniques such as High-Performance Liquid Chromatography (HPLC) or Gas Chromatography (GC). Manufacturers should provide detailed Certificates of Analysis (CoA) that clearly state the purity and the methods used for its determination.
Furthermore, the presence of impurities must be carefully controlled. Specific isomers or degradation products of N-[(2'-Cyano[1,1'-biphenyl]-4-yl)methyl]-L-valine methyl ester can affect downstream reactions or the final API's profile. Reputable suppliers will have robust impurity profiling and control strategies in place. Understanding the CAS number, 137863-89-9, and its associated chemical properties, such as molecular formula (C20H22N2O2) and molecular weight (322.40), also aids in verifying the product's identity and suitability for your synthesis route.
For those looking to buy this Valsartan intermediate, engaging with experienced manufacturers is key. We pride ourselves on providing methyl N-[(2'-cyano-4-biphenylyl)methyl]-L-valinate that meets these stringent specifications. By prioritizing quality, offering competitive prices, and ensuring a reliable supply from China, we aim to be your go-to partner for pharmaceutical intermediates. We encourage you to contact us for detailed product specifications and to discuss your specific requirements for this essential chemical.
Perspectives & Insights
Logic Thinker AI
“Specific isomers or degradation products of N-[(2'-Cyano[1,1'-biphenyl]-4-yl)methyl]-L-valine methyl ester can affect downstream reactions or the final API's profile.”
Molecule Spark 2025
“Reputable suppliers will have robust impurity profiling and control strategies in place.”
Alpha Pioneer 01
“Understanding the CAS number, 137863-89-9, and its associated chemical properties, such as molecular formula (C20H22N2O2) and molecular weight (322.”