The Role of Latanoprost Lactone Diol in Ophthalmic Formulations: A Chemical Perspective
The development of effective ophthalmic medications relies heavily on the quality and properties of their constituent chemical intermediates. Latanoprost Lactone Diol (CAS 145667-75-0) plays a pivotal role in this arena, serving as a key precursor for latanoprost, a vital drug in managing glaucoma. From a chemical perspective, understanding its characteristics is essential for formulators and API manufacturers. As a specialized manufacturer of Latanoprost Lactone Diol, we highlight its importance in creating advanced ophthalmic formulations.
Chemical Properties and Significance
Latanoprost Lactone Diol, with its molecular formula C18H24O4 and a molecular weight of approximately 304.38 g/mol, is a complex organic molecule. Its structure, a phenyl-substituted prostaglandin analog featuring a lactone ring and two hydroxyl groups, dictates its reactivity and suitability for pharmaceutical synthesis. The compound typically presents as a White to Off-White solid, with a melting point around 69-71 °C. Its lipophilic nature is crucial, as it facilitates penetration through biological membranes, a key property for drugs administered to the eye. The precise stereochemistry of Latanoprost Lactone Diol is critical, as it directly translates to the biological activity of the final latanoprost product.
From Intermediate to Ophthalmic Solution
The journey of Latanoprost Lactone Diol from a chemical intermediate to a therapeutic ophthalmic solution involves sophisticated synthesis and formulation processes. As an intermediate, its purity is paramount. Impurities can affect the efficacy of the final drug, lead to unwanted side effects, or complicate the manufacturing process. Therefore, when pharmaceutical companies decide to buy Latanoprost Lactone Diol, they seek a product that meets exacting pharmaceutical standards. Reliable suppliers ensure that the material is produced under controlled conditions, minimizing batch-to-batch variability.
The subsequent conversion of Latanoprost Lactone Diol into latanoprost typically involves esterification and further modifications. The formulated latanoprost is then typically administered as eye drops. The efficacy of these drops in reducing intraocular pressure is directly linked to the quality of the intermediate used. This underscores why selecting a reputable Latanoprost Lactone Diol manufacturer is so important.
Sourcing High-Quality Intermediates
For those involved in ophthalmic formulation and API production, securing a consistent and high-quality supply of Latanoprost Lactone Diol is essential. Our commitment as a leading supplier in China is to provide pharmaceutical-grade intermediates that meet the stringent demands of the industry. We offer competitive pricing and robust quality control to ensure that our clients can confidently develop and manufacture effective treatments for glaucoma and ocular hypertension. If you are looking to purchase Latanoprost Lactone Diol, partner with us for chemical excellence and reliable supply.
Perspectives & Insights
Future Origin 2025
“The subsequent conversion of Latanoprost Lactone Diol into latanoprost typically involves esterification and further modifications.”
Core Analyst 01
“The efficacy of these drops in reducing intraocular pressure is directly linked to the quality of the intermediate used.”
Silicon Seeker One
“This underscores why selecting a reputable Latanoprost Lactone Diol manufacturer is so important.”