As a research scientist, the ability to procure high-quality chiral building blocks is fundamental to the success of advanced organic synthesis projects. (R)-2-Bromobutanoic Acid, identified by CAS number 2681-94-9, stands out as a versatile and essential reagent for creating complex, stereochemically defined molecules. Understanding its chemical characteristics and where to buy it from reliable sources is key for chemists aiming to push the boundaries of synthesis.

Chemical Profile of (R)-2-Bromobutanoic Acid

This compound is characterized as a colorless to light yellow oil liquid, with a notable moisture sensitivity that necessitates careful handling. Its molecular formula is C4H7BrO2, and its molecular weight is approximately 167.00. The guaranteed purity, often 98% or higher, is critical for reactions where precise stereochemistry is required. Its utility as a chiral reagent stems from the bromine atom positioned at the alpha-carbon, making it amenable to various nucleophilic substitution reactions and further functionalization.

Applications in Organic Synthesis Pathways

(R)-2-Bromobutanoic Acid serves as a cornerstone in several synthetic strategies. Its primary use is as a chiral synthon, enabling the introduction of a specific stereocenter into larger molecules. This is particularly relevant in the synthesis of pharmaceutical intermediates, agrochemicals, and specialty fine chemicals where enantiomeric purity directly impacts biological activity or product performance.

  • Asymmetric Synthesis: It's frequently used in constructing chiral centers via enantioselective reactions.
  • Building Blocks for APIs: Many drug molecules incorporate chiral fragments that can be efficiently synthesized using this reagent.
  • Functional Group Transformations: The bromine atom can be readily displaced by various nucleophiles, allowing for the introduction of diverse functional groups.

Sourcing Strategies for Scientists

For scientists needing to buy (R)-2-Bromobutanoic Acid, identifying dependable suppliers is crucial. When you search for a manufacturer or supplier, prioritize those who can provide detailed analytical data, such as NMR spectra, and adhere to stringent quality control measures. Companies offering competitive pricing and reliable shipping from major chemical production regions like China are often excellent choices. Engaging with suppliers who understand the needs of R&D laboratories ensures you receive the right product in appropriate quantities, whether it's for small-scale exploration or larger developmental batches.

By understanding the properties and applications of (R)-2-Bromobutanoic Acid and by partnering with reputable chemical suppliers, researchers can effectively leverage this powerful chiral reagent to accelerate their discovery and development efforts.