In the pharmaceutical industry, precise knowledge of chemical forms and their applications is crucial for successful formulation and manufacturing. Lidocaine, a widely used local anesthetic and antiarrhythmic agent, exists in two primary forms: Lidocaine Base and Lidocaine Hydrochloride (HCl). Understanding the distinctions between these forms is vital for making informed sourcing decisions. This article aims to clarify these differences and guide pharmaceutical buyers in selecting the appropriate form from reliable suppliers.

Lidocaine Base, with the CAS number 137-58-6, is the free amine form of the compound. It is generally less soluble in water compared to its hydrochloride salt. This characteristic can influence its formulation, particularly in solutions where pH plays a significant role. As a pharmaceutical intermediate, Lidocaine Base is often sought for its direct application in certain formulations or as a starting material for synthesis. When searching to buy Lidocaine Base powder online, look for suppliers that guarantee high purity, often exceeding 99%, and adhere to stringent quality standards like USP or BP.

Lidocaine Hydrochloride (HCl), often identified by CAS 6108-05-0 or 73-78-9 for its monohydrate form, is the salt form of Lidocaine. It is more water-soluble, making it ideal for injectable solutions and formulations where rapid dissolution is required. Many topical preparations and injectable anesthetics utilize Lidocaine HCl due to its solubility profile. As a Lidocaine HCl supplier, manufacturers must ensure consistent quality and purity, typically above 99%, to meet pharmaceutical demands.

The choice between Lidocaine Base and Lidocaine HCl often depends on the specific application and formulation requirements. For instance, topical preparations might benefit from the properties of either form depending on the base and desired release profile, while intravenous solutions almost exclusively use the water-soluble HCl salt. Understanding these nuances is key when discussing your needs with a potential pharmaceutical raw material supplier.

When sourcing either form, whether it's Lidocaine Base for sale or Lidocaine HCl, reliability of the manufacturer is paramount. Factors such as consistent batch quality, adherence to GMP standards, and efficient logistics, including fast delivery and secure customs clearance, are critical. A reputable supplier like NINGBO INNO PHARMCHEM CO.,LTD. can provide both high-purity Lidocaine Base and Lidocaine HCl, catering to diverse pharmaceutical needs with expert support.

By understanding the fundamental differences and application-specific advantages of Lidocaine Base and Lidocaine HCl, pharmaceutical buyers can make more informed decisions. Partnering with a knowledgeable and reliable supplier ensures access to the correct, high-quality materials necessary for developing safe and effective pharmaceutical products.