In the pursuit of pharmaceutical innovation, a deep understanding of the chemical and physical properties of key ingredients is non-negotiable. Lidocaine Hydrochloride (HCl) is a prime example of such a compound, widely utilized for its potent local anesthetic and antiarrhythmic capabilities. For R&D scientists and procurement managers, grasping the details of its chemical profile—from molecular structure to appearance—is crucial for effective sourcing and formulation. When you consider where to buy Lidocaine HCl, focusing on suppliers who detail these chemical aspects is a strategic move.

Chemical Identity and Structure of Lidocaine HCl

Lidocaine Hydrochloride is chemically known as 2-(diethylamino)-N-(2,6-dimethylphenyl)-acetamide monohydrochloride monohydrate. Its molecular formula is C14H23ClN2O, and it possesses a molecular weight of approximately 288.82 g/mol. This structure, characterized by an amide linkage connecting a substituted aniline ring to a diethylamino group, is fundamental to its pharmacological activity. The presence of the hydrochloride salt enhances its water solubility, a critical factor for many pharmaceutical applications.

The EINECS number associated with Lidocaine HCl is 200-803-8, providing a standard identifier in chemical inventories. As a high-purity pharmaceutical intermediate, it is typically supplied as a white or almost white crystal powder. This physical characteristic is important for visual quality control during manufacturing and formulation processes.

Purity and Standards: The Foundation of Efficacy

For pharmaceutical use, the purity of Lidocaine HCl is paramount, with specifications often exceeding 99%. Adherence to pharmacopoeial standards, such as USP (United States Pharmacopeia) and BP (British Pharmacopoeia), is a critical requirement. These standards ensure that the ingredient is free from harmful impurities and possesses the precise chemical characteristics needed for therapeutic efficacy and safety. When sourcing from a manufacturer in China, confirming their commitment to these rigorous standards is essential. A reliable Lidocaine HCl powder supplier will readily provide Certificates of Analysis (CoA) detailing purity and compliance.

Physical Properties and Formulation Implications

The physical form of Lidocaine HCl as a white or almost white crystal powder dictates its handling properties in pharmaceutical manufacturing. Its crystalline nature influences its flowability, bulk density, and dissolution rate, all of which can impact formulation processes, especially in solid dosage forms or suspensions. The high water solubility of Lidocaine HCl makes it an ideal choice for:

  • Injectable solutions
  • Aqueous topical preparations
  • Oral solutions and rinses

For formulators working on anhydrous or lipid-based systems requiring better skin penetration, Lidocaine base might be a more suitable choice, though Lidocaine HCl remains the standard for water-soluble applications.

Procurement and Partnership

When looking to purchase Lidocaine HCl, partnering with a reputable pharmaceutical intermediate supplier is key. A knowledgeable manufacturer will not only provide materials that meet strict chemical and physical specifications but can also offer insights into handling, stability, and compatibility. Exploring wholesale supply options from trusted sources ensures both quality and cost-effectiveness. Engaging with a top-tier supplier for your Lidocaine HCl needs sets the stage for successful product development and consistent manufacturing.

By understanding the detailed chemical profile of Lidocaine HCl, pharmaceutical professionals can confidently select and utilize this vital compound, driving innovation in anesthesia and cardiac therapies.