Lidocaine Hydrochloride (CAS 73-78-9) is a foundational ingredient for numerous pain management solutions, primarily due to its efficacy as a local anesthetic. Its ability to reversibly block nerve conduction makes it indispensable for pharmaceutical formulators aiming to alleviate pain and discomfort.

The most common application of Lidocaine Hydrochloride in pain management is through topical formulations. These include creams, gels, ointments, sprays, and patches designed for localized relief. These products are formulated to deliver the anesthetic directly to the affected skin or mucous membranes, targeting pain associated with minor skin irritations, burns, insect bites, cuts, and scrapes. The concentration and excipients used in these formulations are critical for ensuring proper skin penetration, efficacy, and patient comfort.

For example, Lidocaine Hydrochloride creams are widely used to soothe sunburned skin or minor burns, providing quick relief from stinging and itching. Gels and ointments can be particularly effective for delivering the anesthetic to deeper skin layers or mucous membranes, aiding in the management of conditions like hemorrhoids or urethritis. Patches offer a sustained release of Lidocaine Hydrochloride, providing prolonged pain relief, often used for conditions like postherpetic neuralgia (shingles pain).

Formulators must consider several factors when developing Lidocaine Hydrochloride-based pain management products. The choice of base (e.g., water-based gel, oil-in-water emulsion cream) significantly impacts drug delivery and skin feel. Solubility, stability, and compatibility with other excipients are also crucial. Furthermore, ensuring that the final product meets rigorous quality standards, such as USP36, is paramount for patient safety and regulatory approval.

Procurement of high-quality Lidocaine Hydrochloride is the first step for any formulator. Buyers often search for terms like 'lidocaine hydrochloride supplier', 'lidocaine hydrochloride manufacturer', and 'buy lidocaine hcl' to identify reliable sources. Competitive lidocaine hydrochloride price from a trusted Chinese manufacturer can significantly impact the cost-effectiveness of the final product, provided quality is not compromised. Always request COAs and inquire about manufacturing practices to ensure the material is suitable for pharmaceutical use.

In essence, Lidocaine Hydrochloride remains a key active pharmaceutical ingredient for creating effective pain relief formulations. By understanding its properties, application mechanisms, and sourcing the right material from reliable suppliers, formulators can develop products that significantly improve patients' quality of life.