In the intricate world of pharmaceutical manufacturing, the quality and consistency of intermediates directly impact the efficacy and safety of the final drug product. M-(1-Cyanoethyl)benzoic acid, identified by CAS number 5537-71-3, plays a pivotal role as a key intermediate, particularly in the synthesis of ketoprofen. For R&D scientists and procurement managers, understanding this compound's importance and sourcing it efficiently is crucial.

The Significance of M-(1-Cyanoethyl)benzoic Acid in Ketoprofen Synthesis

Ketoprofen is a widely prescribed non-steroidal anti-inflammatory drug (NSAID) known for its analgesic, anti-inflammatory, and antipyretic properties. The chemical pathway to synthesize ketoprofen often involves M-(1-Cyanoethyl)benzoic acid as a direct precursor. This means that the purity and availability of this intermediate are critical for a streamlined and successful manufacturing process. A high-purity grade, typically 99% or above, ensures that downstream reactions proceed efficiently, minimizing by-products and maximizing the yield of the active pharmaceutical ingredient.

Sourcing High-Quality Intermediates: A Buyer's Perspective

When looking to purchase M-(1-Cyanoethyl)benzoic acid, buyers are often seeking reliable manufacturers that can supply the compound consistently and at competitive prices. China is a prominent source for such pharmaceutical intermediates. When you reach out to suppliers, it's important to inquire about:

  • Purity Levels: Ensure it meets the required pharmaceutical grade (e.g., ≥99.0%).
  • Appearance: It should be a white or off-white powder.
  • Packaging: Standard packaging is usually 25kg fiber drums, but confirm suitability for your needs.
  • Pricing: Request detailed quotes, specifying quantities and delivery terms.
  • Supplier Reputation: Look for established manufacturers with a history of quality and reliability.

A good supplier will also readily provide essential documentation such as Certificates of Analysis (CoA) and Safety Data Sheets (SDS) to support your internal quality control and regulatory compliance efforts.

Applications and Future Potential

While its role in ketoprofen production is its primary application, the chemical structure of M-(1-Cyanoethyl)benzoic acid also positions it as a valuable organic building block for other research and development projects in the pharmaceutical and potentially agrochemical sectors. Its specific reactivity can be exploited to create novel compounds with targeted biological activities.

For any organization involved in the synthesis of ketoprofen or exploring new chemical entities, securing a dependable supply of M-(1-Cyanoethyl)benzoic acid is a strategic imperative. Engaging with reputable manufacturers and suppliers, especially those offering competitive pricing from China, is the best approach to meet these needs.