Cross-coupling reactions have revolutionized organic synthesis, enabling the efficient formation of carbon-carbon and carbon-heteroatom bonds, which are critical for building complex molecules. Among the key aryl halides utilized in these powerful transformations, 2-Bromo-N,N-dimethylaniline (CAS 698-00-0) stands out as a particularly versatile intermediate. As a leading manufacturer and supplier of fine chemicals, we understand the significance of this compound and are dedicated to providing high-quality material to facilitate your synthetic endeavors.

The strategic placement of the bromine atom on the aromatic ring of 2-Bromo-N,N-dimethylaniline makes it an excellent substrate for palladium-catalyzed cross-coupling reactions. Its participation in Suzuki-Miyaura couplings, for instance, allows for the efficient union with organoboron compounds, leading to the formation of biaryl systems, which are common motifs in pharmaceuticals and advanced materials. Similarly, in Heck reactions, it can be coupled with alkenes to introduce vinyl groups, while Sonogashira coupling with alkynes creates substituted alkynes. The dimethylamino group can also influence the electronic properties of the molecule, sometimes enhancing reactivity or directing regioselectivity in subsequent reactions. If your work involves these critical C-C bond formations, you should consider where to buy 2-Bromo-N,N-dimethylaniline to ensure optimal results.

When selecting a 2-Bromo-N,N-dimethylaniline supplier in China, several factors are critical for ensuring success in these advanced reactions. Foremost among these is product purity. Our 2-Bromo-N,N-dimethylaniline typically boasts an assay of ≥98.0%, which is essential for the effectiveness and selectivity of cross-coupling catalysis. Impurities can poison catalysts, lead to side reactions, and complicate purification. Therefore, sourcing from a reliable manufacturer that guarantees high purity is paramount. Many clients seek the best 2-Bromo-N,N-dimethylaniline price, but the true value lies in the combination of competitive cost and consistent, high-quality material that guarantees reproducible reaction performance.

The physical characteristics of 2-Bromo-N,N-dimethylaniline, such as its light yellow liquid appearance and a density of around 1.4 g/cm³, make it practical for laboratory and industrial handling. Its boiling point of approximately 225.9 °C at 760 mmHg means it can be used in reactions requiring elevated temperatures without excessive volatility. These properties, combined with its reactivity, make it a dependable intermediate for a wide array of synthetic targets, from drug discovery to material science. For companies that need to order 2-Bromo-N,N-dimethylaniline regularly, securing a consistent supply from a trusted source is vital for maintaining project momentum.

The versatility of 2-Bromo-N,N-dimethylaniline extends to its use in other transformations, such as amination reactions or as a precursor to more complex organometallic reagents. Its ability to serve as a starting material in multiple synthetic strategies underscores its importance in modern organic chemistry.

As a leading 2-Bromo-N,N-dimethylaniline manufacturer, we are committed to empowering synthetic chemists with high-quality materials. We encourage researchers and procurement specialists to leverage our expertise and reliable supply chain. Contact us today to discuss your cross-coupling reaction needs and to obtain a quotation for 2-Bromo-N,N-dimethylaniline. Partner with us for seamless synthesis and exceptional results.