For research scientists and synthetic chemists, the availability of versatile and reactive building blocks is fundamental to innovation. 4-Bromophenol (CAS: 106-41-2) stands out as a cornerstone intermediate in organic synthesis, offering a unique combination of functional groups that enable a wide range of chemical transformations. As a dedicated manufacturer and supplier in China, we are committed to providing researchers with the high-quality 4-Bromophenol necessary to push the boundaries of chemical discovery.

The Reactivity Profile of 4-Bromophenol

4-Bromophenol is a crystalline solid with a molecular formula C6H5BrO. Its key feature is the hydroxyl group and the bromine atom positioned at opposite ends of the benzene ring. This para-substitution significantly influences its reactivity. The hydroxyl group is an activating and ortho, para-directing group for electrophilic aromatic substitution, while the bromine atom can participate in various coupling reactions and nucleophilic substitutions. This duality makes it an exceptionally useful reagent in complex synthetic pathways. Researchers often seek out organic synthesis intermediate 4-bromophenol for its predictable behavior and versatile applications.

Key Reactions and Applications in the Lab

The applications of 4-Bromophenol in laboratory synthesis are extensive:

  • Coupling Reactions: It readily participates in palladium-catalyzed cross-coupling reactions such as the Suzuki-Miyaura, Heck, and Sonogashira couplings, allowing for the formation of new carbon-carbon bonds with aryl or vinyl partners. This is critical for building complex molecular architectures.
  • Ether and Ester Formation: The phenolic hydroxyl group can be readily converted into ethers and esters, providing pathways to a variety of functionalized compounds.
  • Electrophilic Substitution: While the ring is activated by the hydroxyl group, further electrophilic substitutions can occur under controlled conditions, albeit with consideration for steric hindrance and directing effects.
  • Precursor for Pharmaceuticals and Agrochemicals: As discussed in other contexts, its use as a starting material for developing pharmaceutical intermediates and agrochemicals is a major driver of its demand.

When seeking to buy 4-bromophenol for your research, understanding its reactivity is crucial for designing efficient synthetic routes.

Sourcing High-Purity 4-Bromophenol

As a reputable CAS 106-41-2 manufacturer, we ensure that the 4-Bromophenol we provide meets the stringent purity requirements of advanced research. High purity is essential to avoid side reactions and ensure the reliability of experimental results. We offer detailed specifications and support for our product, making us a trusted 4-bromophenol supplier in China for academic institutions and industrial R&D departments worldwide. We also provide competitive 4-bromophenol price information for various quantities.

Factors to Consider When Procuring 4-Bromophenol

When ordering 4-Bromophenol, researchers should consider the required purity grade, quantity, and the supplier's ability to provide technical documentation such as Certificates of Analysis (CoA) and Safety Data Sheets (SDS). Our commitment as a premier 4-bromophenol manufacturer means we supply comprehensive documentation to support your work. Furthermore, timely delivery is critical for ongoing experiments, and we pride ourselves on our efficient logistics and customer service.

Conclusion

4-Bromophenol remains an indispensable tool for organic chemists. Its versatile reactivity, coupled with its utility in synthesizing valuable downstream products, makes it a staple in research laboratories. We encourage researchers to leverage our capabilities as a reliable 4-bromophenol supplier to source high-quality material for their groundbreaking work. Contact us to discuss your specific research needs and to obtain a quote.