In the dynamic field of organic synthesis, access to versatile and reactive building blocks is crucial for innovation. 5-Bromo-2-fluoro-4-methylpyridine (CAS: 864830-16-0) stands out as a valuable heterocyclic compound, extensively utilized by chemists for its unique reactivity and potential in creating complex organic molecules.

The chemical structure of 5-Bromo-2-fluoro-4-methylpyridine is characterized by a pyridine ring substituted with a bromine atom at the C-5 position, a fluorine atom at C-2, and a methyl group at C-4. This specific arrangement of functional groups confers distinct chemical properties. The bromine atom serves as an excellent leaving group, making it highly susceptible to a variety of cross-coupling reactions, including Suzuki-Miyaura, Stille, and Sonogashira couplings. These reactions are fundamental for carbon-carbon bond formation and are widely employed in constructing intricate molecular frameworks.

Furthermore, the electron-withdrawing nature of the fluorine atom influences the electron density of the pyridine ring, potentially activating it for nucleophilic aromatic substitution reactions under specific conditions. The methyl group can also be a site for further chemical modifications. These properties make 5-Bromo-2-fluoro-4-methylpyridine a highly sought-after intermediate for chemists engaged in diverse synthetic endeavors, from developing new materials to synthesizing biologically active compounds.

For researchers and industrial chemists looking to buy 5-bromo-2-fluoro-4-methylpyridine, understanding its physical and chemical characteristics is important. It is typically supplied as a colorless to light yellow liquid, with reported boiling points around 208.9°C at 760 mmHg. Its solubility in common organic solvents facilitates its use in various reaction media.

When sourcing this essential intermediate, identifying a reliable 5-bromo-2-fluoro-4-methylpyridine manufacturer or supplier is key to ensuring the success of your synthesis projects. Companies are often searching for the best price of 5-bromo-2-fluoro-4-methylpyridine, balancing cost with the required purity and supply reliability. Many opt for sourcing from manufacturers in China, known for their robust production capabilities in fine chemicals.

In summary, 5-Bromo-2-fluoro-4-methylpyridine is an indispensable tool for modern organic chemists. Its rich reactivity profile makes it a versatile platform for innovation, enabling the synthesis of a wide array of target molecules. Engaging with reputable suppliers ensures access to this critical building block, facilitating groundbreaking research and development.