Mastering Organic Synthesis: Ethyl Oxalyl Monochloride as a Key Reagent
In the intricate world of organic synthesis, the selection of the right reagents can dramatically influence the success of a chemical transformation. Ethyl Oxalyl Monochloride (CAS 4755-77-5), also known by synonyms such as ethyl chlorooxoacetate or ethoxalyl chloride, is a potent and versatile reagent that plays a significant role in creating complex organic molecules.
This compound's chemical structure makes it an excellent source for introducing the chlorocarbonyl group, a highly reactive functional group. This reactivity is leveraged in numerous synthetic pathways. For instance, it is widely used in the preparation of alpha-keto esters, which are foundational units in many organic compounds, including pharmaceuticals and natural products. Its application in Friedel–Crafts acylation reactions also allows for the synthesis of substituted arylglyoxylic acids, further broadening its utility.
Researchers and industrial chemists looking to buy Ethyl Oxalyl Monochloride often seek high-purity grades (typically ≥98.0%) to ensure predictable and efficient reactions. A reliable supplier will not only provide this assurance but also offer comprehensive technical data, such as CAS 4755-77-5 and detailed safety information. Sourcing from manufacturers with a proven track record, especially those in China, can offer cost advantages and reliable supply chains for bulk purchases.
The synthesis of substituted 9,10-phenanthrenequinones and various quinoxalinone derivatives are other notable applications where Ethyl Oxalyl Monochloride proves invaluable. Its role extends to the synthesis of oxyoxalamide derivatives, which have been explored for their potential as epoxide hydrolase inhibitors, highlighting its importance in medicinal chemistry research.
For procurement managers or R&D scientists, identifying a dependable manufacturer for this reagent is crucial. Companies like NINGBO INNO PHARMCHEM CO.,LTD. are dedicated to providing high-quality chemical intermediates. Obtaining a quote for Ethyl Oxalyl Monochloride allows you to assess pricing and availability, ensuring you have a trusted source for your critical organic synthesis projects. Its wide-ranging applications make it a staple reagent for any modern synthetic chemist's toolkit.
Perspectives & Insights
Agile Reader One
“Sourcing from manufacturers with a proven track record, especially those in China, can offer cost advantages and reliable supply chains for bulk purchases.”
Logic Vision Labs
“The synthesis of substituted 9,10-phenanthrenequinones and various quinoxalinone derivatives are other notable applications where Ethyl Oxalyl Monochloride proves invaluable.”
Molecule Origin 88
“Its role extends to the synthesis of oxyoxalamide derivatives, which have been explored for their potential as epoxide hydrolase inhibitors, highlighting its importance in medicinal chemistry research.”