For organic chemists and synthesis specialists, the ability to efficiently construct complex molecular architectures is key to driving innovation. 3-Amino-5-bromopyridine (CAS: 13535-01-8) is a highly valuable heterocyclic building block renowned for its versatility in organic synthesis. Its dual functionality, featuring an amenable amino group and a reactive bromine atom on a pyridine ring, enables a broad spectrum of transformations, including crucial cross-coupling reactions. Procurement managers seeking reliable sources for essential reagents will find this compound indispensable. We are a prominent manufacturer and supplier of high-purity 3-Amino-5-bromopyridine, supporting your synthetic endeavors.

The bromine atom on the pyridine ring makes 3-Amino-5-bromopyridine an excellent substrate for palladium-catalyzed cross-coupling reactions. These reactions are foundational in modern organic chemistry, allowing for the formation of new carbon-carbon and carbon-heteroatom bonds with high selectivity and yield. For instance, the Suzuki-Miyaura coupling can be employed to introduce aryl or vinyl groups at the 5-position, creating complex biaryl systems or vinyl-substituted pyridines. Similarly, Buchwald-Hartwig amination allows for the efficient formation of carbon-nitrogen bonds, introducing diverse amine functionalities. These reactions are critical for building the complex scaffolds found in pharmaceuticals and agrochemicals.

The amino group at the 3-position offers additional synthetic handles. It can undergo acylation, alkylation, or serve as a directing group for further electrophilic aromatic substitutions. This dual reactivity allows chemists to elaborate the molecule in multiple directions, generating a wide array of derivatives. Whether you are involved in creating pharmaceutical intermediates, agrochemical active ingredients, or novel materials, the synthetic potential of 3-Amino-5-bromopyridine is immense. For researchers needing to buy 3-Amino-5-bromopyridine, partnering with a reliable chemical supplier is crucial for consistent quality and delivery.

Metal-halogen exchange reactions are also a common pathway for functionalizing this compound. While the presence of the acidic amino group can pose challenges, strategic use of reagents like Grignard reagents in combination with organolithiums can facilitate efficient bromine-metal exchange, leading to organometallic intermediates that can then react with various electrophiles. This opens up pathways for introducing diverse functional groups onto the pyridine ring.

For organizations requiring this versatile building block, sourcing from a reputable manufacturer in China ensures competitive CAS 13535-01-8 chemical price and dependable supply. We pride ourselves on offering high-purity 3-Amino-5-bromopyridine, backed by rigorous quality control. Empower your organic synthesis projects by choosing us as your trusted chemical partner.