Organic synthesis is the cornerstone of modern chemistry, enabling the creation of novel materials, life-saving medicines, and essential agricultural products. At the heart of successful synthesis lie versatile chemical intermediates – molecules that serve as precise building blocks for more complex structures. Among these, halogenated and fluorinated aromatic amines are particularly valuable due to their unique reactivity and the desirable properties they impart to final compounds. 3-Chloro-4-fluoro-5-(trifluoromethyl)aniline (CAS: 914225-61-9) exemplifies such a crucial intermediate, offering chemists a powerful tool for innovation.

The molecular architecture of 3-Chloro-4-fluoro-5-(trifluoromethyl)aniline is designed for reactivity and adaptability. The aniline core provides a nucleophilic amine group, while the strategically placed chlorine, fluorine, and trifluoromethyl substituents profoundly influence the electron density and steric profile of the aromatic ring. This combination makes it an excellent starting material for a variety of chemical transformations, including electrophilic aromatic substitution, nucleophilic aromatic substitution (under specific conditions), and coupling reactions. For professionals seeking to buy organic synthesis intermediates, understanding the capabilities of such compounds is key.

The trifluoromethyl group (-CF3) is especially significant. Its strong electron-withdrawing nature can activate or deactivate specific positions on the aromatic ring, guiding regioselectivity in subsequent reactions. Furthermore, the -CF3 group is known to enhance the lipophilicity and metabolic stability of molecules, properties highly desired in pharmaceuticals and agrochemicals. When you purchase 3-Chloro-4-fluoro-5-(trifluoromethyl)aniline, you are acquiring a building block that can confer these advantageous characteristics to your target compounds.

Chemists often rely on intermediates with guaranteed purity to achieve reproducible results. With a typical assay purity of ≥99.0% by HPLC and a low moisture content (≤0.5%), this compound ensures that side reactions are minimized and yields are maximized. For those looking for a consistent supply of high-quality C7H4ClF4N, sourcing from a reliable manufacturer in China is a strategic choice. These suppliers are equipped to handle the complex synthesis and purification processes required for such specialized chemicals.

The applications of 3-Chloro-4-fluoro-5-(trifluoromethyl)aniline are diverse. It is widely used in the development of pharmaceuticals, contributing to the creation of molecules with improved pharmacokinetic profiles. In agrochemicals, it aids in synthesizing potent herbicides and pesticides. Its unique properties also find utility in the field of material science, where it can be incorporated into specialty polymers or functional materials. For any scientist or procurement specialist, identifying a dependable CAS 914225-61-9 supplier is crucial for ensuring project success. By leveraging the capabilities of leading chemical producers, you can confidently integrate this versatile intermediate into your synthetic pathways.